國家衛生研究院 NHRI:Item 3990099045/6557
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    题名: Changes of serum adiponectin and soluble intercellular adhesion molecule-1 concentrations after smoking cessation
    作者: Tsai, JS;Guo, FR;Chen, SC;Lue, BH;Lee, LT;Huang, KC;Chen, CY;Hung, SH;Chuang, LM
    贡献者: Division of Geriatric Research
    摘要: Background: This study aims to investigate the effect of increased serum adiponectin concentration during smoking cessation on soluble intercellular adhesion molecule-1 (sICAM-1) concentration. Methods: One hundred and sixty-six eligible smokers were assessed at baseline and were followed up at the 1st, 5th, and 9th weeks after smoking cessation. Demographic data, body weight and blood pressure of these participants were obtained; serum glucose biochemical data, sICAM-1 and adiponectin concentrations were measured. Repeated measures analysis paired t-tests and generalized estimating equations for balanced repeated measures were used for statistical analyses. Results: Forty-one individuals completed the 2-month smoking cessation program. The mean cigarette consumption dramatically decreased (p<0.0001) and the cotinine concentration also decreased significantly (p<0.0001) among the quitters. Serum adiponectin concentration significantly increased (p=0.0186) and sICAM-1 significantly decreased (p<0.0001) in quitters after smoking cessation. The elevation of serum adiponectin concentration significantly correlated with lowering of sICAM-1 (p=0.0001) concentration. Body weight changes at the end of 2-month smoking cessation was inversely correlated with adiponectin increment from baseline (p=0.0003). Conclusions: An increase in serum adiponectin concentration is an independent factor correlated with lowering of sICAM-1 concentration during smoking cessation.
    日期: 2012-06
    關聯: Clinical Chemistry and Laboratory Medicine. 2012 Jun;50(6):1063-1069.
    Link to: http://dx.doi.org/10.1515/cclm-2011-0852
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1434-6621&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000305631600015
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84867419935
    显示于类别:[陳慶餘(2006-2010)] 期刊論文

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