國家衛生研究院 NHRI:Item 3990099045/6305
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    题名: Traffic air pollution and risk of death from ovarian cancer in Taiwan: Fine particulate matter (PM 2.5) as a proxy marker
    作者: Hung, LJ;Chan, TF;Wu, CH;Chiu, HF;Yang, CY
    贡献者: Division of Environmental Health and Occupational Medicine
    摘要: The relationship between mortality attributed to ovarian cancer and exposure to ambient air pollutants was examined using an ecological design. The study areas consisted of 61 municipalities in Taiwan. Air quality data for recorded concentrations of fine particulate matter (PM 2.5) from study municipalities for 2006-2009 were obtained as a marker of traffic emissions. These were used as a proxy for polycyclic aromatic hydrocarbons (PAH) exposure. Age-standardized mortality rates for ovarian cancer were calculated for the study municipalities for the years 1999-2008. A weighted multiple regression model was employed to calculate the adjusted risk ratio (RR) in relation to PM 2.5 levels. After adjusting for urbanization level and fertility rate, the adjusted RR values (95% confidence interval [CI]) for ovarian cancer were 1.2 (1.02-1.41) for the municipalities with PM 2.5 levels between 30.48 μg/m 3 and 39.41 μg/m 3 and 1.2 (1.03-1.39) for the municipalities with PM 2.5 levels between 39.48 μg/m 3 and 51.1 μg/m 3, compared to the municipalities with PM 2.5 levels less than 30.39 μg/m 3. Results showed that individuals who resided in municipalities with higher levels of PM 2.5, a proxy measure of PAH, were at an increased risk of death from ovarian cancer compared to those subjects living in municipalities with the lowest PM 2.5. The findings of this study warrant further investigation into the role of exposure to air pollutants in the etiology of ovarian cancer development.
    日期: 2012-02-01
    關聯: Journal of Toxicology and Environmental Health - Part A: Current Issues. 2012 Feb 1;75(3):174-182.
    Link to: http://dx.doi.org/10.1080/15287394.2012.641200
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1528-7394&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000302184800004
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84863077290
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