國家衛生研究院 NHRI:Item 3990099045/6259

NHRI > National Institute of Infectious Diseases and Vaccinology > Chi-Jung Wu > Periodical Articles > Item 3990099045/6259

Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/6259

Title:	Susceptibilities to Amphotericin B, Fluconazole and Voriconazole of Trichosporon clinical isolates
Authors:	Tsai, MS;Yang, YL;Wang, AH;Wang, LS;Lu, DCT;Liou, CH;Hsieh, LY;Wu, CJ;Cheng, MF;Shi, ZY;Lo, HJ
Contributors:	Division of Infectious Diseases
Abstract:	A total of 35 Trichosporon isolates were collected from the Taiwan Surveillance of Antimicrobial Resistance of Yeasts (TSARY) project from 1999 to 2006, and their identifications as well as drug susceptibilities were determined. The most frequently isolated species was T. asahii (62.9%), and the most common clinical sample that yielded Trichosporon isolates was urine (37.1%). The etiology of all seven invasive trichosporonosis was T. asahii . For the 22 T. asahii isolates, the MIC 50 and MIC 90 for amphotericin B were 0.25 and 1 μg/mL, respectively. Those for fluconazole were 2 and 4 μg/mL, respectively, and for voriconazole 0.031 and 0.063 μg/mL, respectively. When the intraclass correlation coefficients (ICCs) and agreements were calculated, we found that the MICs of fluconazole obtained from different methods were similar and the inter-method discrepancies were low. Nevertheless, no unanimous MIC of amphotericin B and voriconazole was obtained among different methods.
Date:	2012-08
Relation:	Mycopathologia. 2012 Aug;174(2):121-130.
Link to:	http://dx.doi.org/10.1007/s11046-012-9525-z
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0301-486X&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000306125100003
Cited Times(Scopus):	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84864290126
Appears in Collections:	[Chi-Jung Wu] Periodical Articles [Hsiu-Jung Lo] Periodical Articles

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