國家衛生研究院 NHRI:Item 3990099045/6145

NHRI > Institute of Population Health Sciences > MARK LAWRENCE WAHLQVIST(2008-2012) > Periodical Articles > Item 3990099045/6145

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Title:	Prediction of all-cause mortality by B group vitamin status in the elderly
Authors:	Huang, YC;Lee, MS;Wahlqvist, ML
Contributors:	Division of Health Services and Preventive Medicine
Abstract:	Background & aims: Little is known about the direct relationship of B vitamins to mortality in the elderly. All-cause mortality by vitamin B status, using dietary (B-1, B-2, niacin, B-6) or biochemical data (erythrocyte transketolase reductase, erythrocyte glutathione reductase, plasma pyridoxal-phosphate, folate and serum B-12) was evaluated. Methods: The Taiwanese Elderly Nutrition and Health Survey (1999-2000) provided 1747 participants 65 years and over. Dietary and biochemical data were collected at baseline. Survivorship was determined until December 31, 2008. Results: Survivors had higher vitamin B-1 and niacin intakes and pyridoxal-phosphate and folate concentrations. Controlled for confounders, and relative to the lowest tertile of vitamin B-1 or B-6 intakes, the hazard ratios (95% confidence interval) for tertile 3 were 0.74 (0.58-0.95) and 0.74 (0.57-0.97); both p for trend values were <0.05. Further adjustment for dietary diversity led to insignificant findings. For pyridoxal-phosphate, compared to those with deficiency levels, the multivariable-adjusted hazard ratios (95% confidence interval) for adequacy was 0.52 (0.38-0.71) with p for trend <0.0001 and unchanged with dietary diversity adjustment. Conclusions: Higher vitamin B-1 and B-6 intakes and plasma pyridoxal-phosphate were associated with lower risk of mortality up to 10 years and could be achieved by increased dietary diversity.
Date:	2012-04
Relation:	Clinical Nutrition. 2012 Apr;31(2):191-198.
Link to:	http://dx.doi.org/10.1016/j.clnu.2011.10.010
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0261-5614&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000302987200006
Cited Times(Scopus):	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84858748423
Appears in Collections:	[MARK LAWRENCE WAHLQVIST(2008-2012)] Periodical Articles

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