The blaOXA-51-like gene, originally intrinsic to Acinetobacter baumannii, had been detected in two clones of Acinetobacter nosocomialis and one clone of Acinetobacter genomic species ‘Close to 13TU’. These blaOXA-51-like genes, all preceded by ISAba1, were located on plasmids that might be originated from A. baumannii. The plasmid-borne ISAba1- blaOXA-51-like confers a high level of carbapenem resistance, and affects the accuracy of using blaOXA-51-like detection as a tool for differentiating A. baumannii from other Acinetobacter species.
Date:
2012-02
Relation:
Antimicrobial Agents and Chemotherapy. 2012 Feb;56(2):1124-1127.