國家衛生研究院 NHRI:Item 3990099045/6053
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    题名: Size separation of ultrafine PEG-coated polycaprolactone nanoparticle and morphological studies by AFM
    作者: Chu, CH;Wang, YC;Wu, LC;Yang, CS
    贡献者: Center for Nanomedicine Research
    摘要: Novel ultrafine polycaprolactone nanoparticles (PCL NPs) were prepared using poly(ethyleneglycol)2000-distearyl phosphoethanolamine (PEGPE) as the oily phase emulsifier in the emulsion process, resulting in PEG-coated PCL NPs (PEGPE-PCL), which could be reduced and confined in size to below 50 nm. Size separation of PEG-coated polymer NPs remain significant challenges in the preparation for fundamental studies and applications. We used a gel filtration chromatography method for the rapid size separation of PEGPE-PCL and studied the physicochemical characteristics. The morphology of the core-shell PEGPE-PCL on a mica surface followed by NP concentration was observed by atomic force microscopy (AFM). It is important to separate size and define PEGPE-PCL structure for further potential in drug delivery application.
    日期: 2011-09
    關聯: Optoelectronics and Advanced Materials, Rapid Communications. 2011 Sep;5(9):969-972.
    Link to: http://oam-rc.inoe.ro/index.php?option=magazine&op=view&idu=1667&catid=66
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1842-6573&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000297637400017
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=80053899359
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