PEG-400[poly(ethylene glycol-400)] is used as reaction medium in the one-pot synthesis of 6-aryl-imidazo[2,1-b]thiazoles by reaction with aryl ketones, hypervalent iodine(III) sulfonate and 2-amino-thiazole. Significant rate enhancements and improved yields have been observed.
Date:
2011-09
Relation:
Journal of the Chinese Chemical Society. 2011 Sep;58(5):663-666.