Mesoporous titania nanoparticles (MTNs) with excellent biocompatibility (LC50 [approximate] 400 [small mu ]g mL-1) and a large surface area (ca. 237.3 m2 g-1) were synthesized and further functionalized with a phosphate-containing fluorescent molecule (i.e. flavin mononucleotide; FMN) and loaded with an anticancer drug (i.e. Doxorubicin) for successful intracellular bioimaging and drug delivery, respectively, in human breast cancer cells BT-20.
Date:
2011-04
Relation:
Chemical Communications. 2011 Apr;47(18):5232-5234.
