國家衛生研究院 NHRI:Item 3990099045/5599
English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 12145/12927 (94%)
造訪人次 : 912487      線上人數 : 1216
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧：
  • 您可在西文檢索詞彙前後加上"雙引號"，以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋，建議至進階搜尋限定作者欄位，可獲得較完整資料
    •  進階搜尋
    主頁 ‧ 登入 ‧ 上傳 ‧ 說明 ‧ 關於NHRI ‧ 管理 到手機版


    請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/5599


    題名: First total synthesis of the cis-clerodane diterpenoids solidagolactones IV and V
    作者: Liu, HJ;Ho, YL;Shia, KS
    貢獻者: Institute of Biotechnology and Pharmaceutical Research
    摘要: Clerodane diterpenoids are widely distributed in nature and constitute one of the largest and, yet, still rapidly growing family of secondary metabolites. Of the relatively few clerodanes tested for biological activity, many were found to possess interesting antifeedant and medicinal properties and are potentially useful as insecticidal, antitumour, antifungal, antibiotic, antipeptic ulcer, and psychotropic agents. The structural complexity and biological activity associated with this class of natural products have attracted extensive effort towards their total syntheses. In most of the reported syntheses, the synthetic sequence is specific to the target molecule. We have recently developed an efficient general strategy for the synthesis of clerodane diterpenoids of the cis-series. The key ingredient is the face selective Diels-Alder reaction of dienophile 1. The successful application of this strategy has culminated in the first total synthesis of the naturally occurring compounds solidagolactones IV (2) and V (3) in racemic form.
    日期: 2007-03
    關聯: Abstracts of Papers - American Chemical Society. 2007 Mar;233:407-ORGN.
    Link to: http://oasys2.confex.com/acs/233nm/techprogram/P1030001.HTM
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000207722808219
    顯示於類別:[夏克山] 會議論文/會議摘要

    文件中的檔案:

    沒有與此文件相關的檔案.



    在NHRI中所有的資料項目都受到原著作權保護.

    TAIR相關文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋