國家衛生研究院 NHRI:Item 3990099045/5327
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/5327


    Title: Labdanecaryophyllic acid, a novel cytotoxic C35 terpenoid from Calocedrus macrolepis var. formosana
    Authors: Hsien, CL;Tseng, MH;Pan, RN;Chang, JY;Kuo, CC;Lee, TH;Kuo, YH
    Contributors: National Institute of Cancer Research
    Abstract: Chemical investigation of the bark of Calocedrus macrolepis var. formosana, an endemic tree in Taiwan, has led to the isolation of a novel terpenoid 1. Compound 1 with a rare C35 skeleton constructed by a diterpene and a sesquiterpene moieties. Its structure was elucidated by spectroscopic interpretations. The anti-proliferation activity of 1 against human oral epidermoid carcinoma KB cells was evaluated, and the IC50 value was determined to be 9.2 ± 0.4 μM.
    Date: 2011-01-26
    Relation: Tetrahedron Letters. 2011 Jan 26;52(4):515-517.
    Link to: http://dx.doi.org/10.1016/j.tetlet.2010.11.101
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0040-4039&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000286862400012
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=78650519367
    Appears in Collections:[Ching-Chuan Kuo] Periodical Articles
    [Jang-Yang Chang] Periodical Articles

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