Siblings 會議論文/會議摘要 [1/3] Collection Statistics 近3年內發表的文件:7(33.33%) 含全文筆數:21(100.00%) 文件下載次數統計 下載大於0次:21(100.00%) 下載大於100次:19(90.48%) 檔案下載總次數:9004(94.76%) 最後更新時間: 2024-12-01 11:00 上傳排行 資料載入中..... 下載排行 資料載入中..... 最近上傳 DBPR116, a prodrug of BPRMU191, in ... Discovery of a mu-opioid receptor m... Analysis of structure–activity rela... A dual nociceptin and mu opioid rec... Benzo[b]thiophene-2-carboxamides as... Selective and antagonist-dependent ... Discovery and development of a nove... Comparative study between deep lear... Unique sulfur-aromatic interactions... BPR1M97, a dual mu opioid receptor/...

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日期	題名	關聯
2024-10-29	DBPR116, a prodrug of BPRMU191, in combination with naltrexone as a safer opioid analgesic than morphine via peripheral administration	Journal of Medicinal Chemistry. 2024 Oct 29;Article in Press.
2024-07-17	Discovery of a mu-opioid receptor modulator that in combination with morphinan antagonists induces analgesia	Cell Chemical Biology. 2024 Jul 17;Article in Press.
2023-11-15	Analysis of structure–activity relationship of indol-3-yl-N-phenylcarbamic amides as potent STING inhibitors	Bioorganic and Medicinal Chemistry. 2023 Nov 15;95:Article number 117502.
2023-10-05	A dual nociceptin and mu opioid receptor agonist exhibited robust antinociceptive effect with decreased side effects	European Journal of Medicinal Chemistry. 2023 Oct 05;258:Article number 115608.
2022-12-05	Benzo[b]thiophene-2-carboxamides as novel opioid receptor agonists with potent analgesic effect and reduced constipation	European Journal of Medicinal Chemistry. 2022 Dec 5;243:Article number 114728.
2022-11	Selective and antagonist-dependent µ-opioid receptor activation by the combination of 2-{[2-(6-chloro-3,4-dihydro-1(2H)-quinolinyl)-2-oxoethyl]sulfanyl}-5-phenyl-4,6-(1H,5H)-pyrimidinedione and naloxone/naltrexone	Bioorganic Chemistry. 2022 Nov;128:Article number 105905.
2022-02-05	Discovery and development of a novel N-(3-bromophenyl)-{[(phenylcarbamoyl)amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug design	European Journal of Medicinal Chemistry. 2022 Feb 5;229:Article number 114043.
2020-10-08	Comparative study between deep learning and QSAR classifications for TNBC inhibitors and novel GPCR agonist discovery	Scientific Reports. 2020 Oct 8;10:Article number 16771.
2020-04	BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, produces potent antinociceptive effects with safer properties than morphine	Neuropharmacology. 2020 Apr;166:Article number 107678.
2020-02-10	Unique sulfur-aromatic interactions contribute to the binding of potent imidazothiazole indoleamine 2,3-Dioxygenase inhibitors	Journal of Medicinal Chemistry. 2020 Feb 10;63(4):1642-1659.

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