| 2011-12 |
Development of a whole-cell screening system for evaluation of the human CYP1A2-mediated metabolism |
Biotechnology and Bioengineering. 2011 Dec;108(12):2932-2940. |
 |
| 2011-08 |
BPR1K653, a novel aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells |
PLoS ONE. 2011 Aug;6(8):Article number e23485. |
|
| 2011-07 |
Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) |
Bioorganic and Medicinal Chemistry. 2011 Jul;19(14):4173-4182 . |
|
| 2011-06-01 |
Suppression of Stat3 activity sensitizes gefitinib-resistant non small cell lung cancer cells |
Biochemical Pharmacology. 2011 Jun 01;81(11):1263-1270. |
|
| 2011-06 |
Synergistic inhibition of enterovirus 71 replication by interferon and rupintrivir |
Journal of Infectious Diseases. 2011 Jun;203(12):1784-1790. |
|
| 2011-04-25 |
Diosgenin, a plant-derived sapogenin, exhibits antiviral activity in vitro against hepatitis C virus |
Journal of Natural Products. 2011 Apr 25;74(4):580-584. |
|
| 2011-04 |
Isatin-beta-thiosemicarbazones as potent herpes simplex virus inhibitors |
Bioorganic and Medicinal Chemistry Letters. 2011 Apr;21(7):1948-1952. |
|
| 2011-02 |
Synthesis of 3,3-dimethylglutamic acid derivatives as DPP-IV inhibitors and evaluation of their chemical stability |
Journal of the Chinese Chemical Society. 2011 Feb;58(1):108-117. |
|
| 2010-10-28 |
Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and michael acceptor group for maximal potency |
Journal of Medicinal Chemistry. 2010 Oct 28;53(20):7316-7326. |
|
| 2010-10 |
Structural basis for the improved potency of peroxisome proliferator-activated receptor (PPAR) agonists |
ChemMedChem. 2010 Oct;5(10):1707-1716. |
|
| 2010-06-15 |
Fast-forwarding hit to lead: Aurora and epidermal growth factor receptor kinase inhibitor lead identification |
Journal of Medicinal Chemistry. 2010 Jun 15;53(13):4980-4988. |
|
| 2010-04 |
Inhibition of enterovirus 71 replication and the viral 3D polymerase by aurintricarboxylic acid |
Journal of Antimicrobial Chemotherapy. 2010 Apr;65(4):676-683. |
|
| 2010-02-23 |
Pyrazole compound BPR1P0034 with potent and selective anti-influenza virus activity |
Journal of Biomedical Science. 2010 Feb 23;17:Article number 13. |
|
| 2010-02-01 |
Identification, SAR studies, and X-ray Co-crystallographic analysis of a novel furanopyrimidine aurora kinase a inhibitor |
ChemMedChem. 2010 Feb 1;5(2):255-267. |
|
| 2010-01 |
BPR2-D2 targeting viral ribonucleoprotein complex-associated function inhibits oseltamivir-resistant influenza viruses |
Journal of Antimicrobial Chemotherapy. 2010 Jan;65(1):63-71. |
|
| 2009-11-01 |
Design and efficient synthesis of novel arylthiourea derivatives as potent hepatitis C virus inhibitors |
Bioorganic and Medicinal Chemistry Letters. 2009 Nov 1;19(21):6063-6068. |
|
| 2009-11 |
Development of NS3/4A protease-based reporter assay suitable for efficiently assessing hepatitis C virus infection |
Antimicrobial Agents and Chemotherapy. 2009 Nov;53(11):4825-4834. |
|
| 2009-08-01 |
Design and synthesis of indole, 2,3-dihydro-indole, and 3,4-dihydro-2H-quinoline-1-carbothioic acid amide derivatives as novel HCV inhibitors |
Bioorganic and Medicinal Chemistry Letters. 2009 Aug 1;19(15):4134-4138. |
|
| 2009-07 |
Novel antiviral agent DTriP-22 targets RNA-dependent RNA polymerase of enterovirus 71 |
Antimicrobial Agents and Chemotherapy. 2009 Jul;53(7):2740-2747. |
|
| 2009-04-23 |
Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists |
Journal of Medicinal Chemistry. 2009 Apr 23;52(8):2618-2622. |
|
| 2009-04-01 |
Design, synthesis, and anti-HCV activity of thiourea compounds |
Bioorganic and Medicinal Chemistry Letters. 2009 Apr 1;19(7):1950-1955. |
|
| 2009-02-26 |
Structure-based drug design of novel aurora kinase a inhibitors: Structural basis for potency and specificity |
Journal of Medicinal Chemistry. 2009 Feb 26;52(4):1050-1062. |
|
| 2009-02 |
Aurintricarboxylic acid inhibits influenza virus neuraminidase |
Antiviral Research. 2009 Feb;81(2):123-131. |
|
| 2008-12 |
Mana-Hox displays anticancer activity against prostate cancer cells through tubulin depolymerization and DNA damage stress |
Naunyn-Schmiedeberg's Archives of Pharmacology. 2008 Dec;378(6):599-608. |
|
| 2008-11 |
Amantadine as a regulator of internal ribosome entry site |
Acta Pharmacologica Sinica. 2008 Nov;29(11):1327-1333. |
|
