國家衛生研究院 NHRI:Item 3990099045/4838

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Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/4838

Title:	A voxel-based partial volume correction in nuclear medicine
Other Titles:	Medical Imaging 2006: Image Processing
Authors:	Huang, HM;Hsiao, IT;Wietholt, C;Hsu, CH
Contributors:	Division of Medical Engineering Research
Abstract:	Most partial volume correction (PVC) methods are ROI-based, and assume uniform activity within each ROI. Here, we extended a PVC method, developed by Roussel et al (JNM, 1998) called geometric transfer matrix (GTM), to a voxel-based PVC approach called v-GTM which accounts non-uniform activity within each ROI. The v-GTM method was evaluated using simulated data (perfect co-registered MRIs). We investigated the influence of noise, the effect of compensating detector response during iterative reconstruction methods and the effect of non-uniform activity. For simulated data, noise did not affect the accuracy of v-GTM method seriously. When detector response compensation was applied in iterative reconstruction, both PVC methods did not improve the recovery values. In the non-uniform experiment, v-GTM had slightly better recovery values and less bias than those of GTM. Conclusion: v-GTM resulted better recovery values, and might be useful for PVC in small regions of interest.
Date:	2006-03
Relation:	Proceedings of the Society of Photo-Optical Instrumentation Engineers(SPIE). 2006;6144(Part 1-3):P1446.
Link to:	http://dx.doi.org/10.1117/12.654273
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000238033302075
Cited Times(Scopus):	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=33745123336
Appears in Collections:	[Others] Conference Papers/Meeting Abstract

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