國家衛生研究院 NHRI:Item 3990099045/4607
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    题名: Hyperuricemia and metabolic syndrome in the middle aged in Taiwan
    作者: Shen, YH;Hsu, CM;Chen, YF;Chen, CY;Yao, CA;Lee, LT;Huang, KC
    贡献者: Division of Gerontology Research
    摘要: Objectives: The relationship between serum uric acid levels and cardiovascular risk factors is complex. We examined the association between hyperuricemia and metabolic syndrome amongst apparently healthy Taiwanese aged from forty to sixty-five years. Research Design And Methods: This cross-sectional survey was based on a population from 4 nationwide health screening centers in Taiwan in 2000. A total of 4,466 subjects, aged 40 to 65 years were included. Blood pressure, body mass index (BMI), waist circumference, HDL cholesterol, serum triglycerides, and uric acid levels were measured. Hyperuricemia was defined as a serum uric acid level > or = 7.0 mg/dl (420 µmol/L) in men and > or = 6.0 mg/dl (360 µmol/L) in women, respectively. Metabolic syndrome was defined using the National Cholesterol Education Panel (NCEP) criteria or modified NCEP criteria (WC >90 cm in men and >80 cm in women).Results: The prevalence of hyperuricemia was 42.4% in men and 28.7% in women, respectively. The crude odds ratios (ORs) of metabolic syndrome was 2.79 (and 2.68 using the modified NCEP criteria) in subjects with hyperuricemia with increasing age (OR = 1.01-1.10) and BMI (OR = 1.39-1.47), the ORs of having metabolic syndrome increased significantly in each gender. After adjustment for age, gender, and BMI, the ORs of metabolic syndrome were significantly higher in subjects with hyperuricemia. Consclusions: The present study revealed that hyperuricemia was positively associated with metabolic syndrome and its individual factors. Therefore, serum uric acid levels may be applied as an additional evaluation for metabolic syndrome in a clinical setting.
    日期: 2008-05
    關聯: International Journal of Obesity. 2008 May;32(Suppl. 1):S138.
    Link to: http://dx.doi.org/10.1038/ijo.2008.47
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0307-0565&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000255820100546
    显示于类别:[陳慶餘(2006-2010)] 會議論文/會議摘要

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