國家衛生研究院 NHRI:Item 3990099045/4578

NHRI > Institute of Biomedical Engineering and Nanomedicine > Ned H. C. Hwang(2000-2008) > Conference Papers/Meeting Abstract > Item 3990099045/4578

Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/4578

Title:	Cavitation behavior observed in three monoleaflet mechanical heart valves under accelerated testing conditions
Authors:	Lo, CW;Liu, JS;Li, CP;Lu, PC;Hwang, NH
Contributors:	Division of Medical Engineering Research
Abstract:	Accelerated testing provides a substantial amount of data on mechanical heart valve durability in a short period of time, but such conditions may not accurately reflect in vivo performance. Cavitation, which occurs during mechanical heart valve closure when local flow field pressure decreases below vapor pressure, is thought to play a role in valve damage under accelerated conditions. The underlying flow dynamics and mechanisms behind cavitation bubble formation are poorly understood. Under physiologic conditions, random perivalvular cavitation is difficult to capture. We applied accelerated testing at a pulse rate of 600 bpm and transvalvular pressure of 120 mm Hg, with synchronized videographs and high-frequency pressure measurements, to study cavitation of the Medtronic Hall Standard (MHS), Medtronic Hall D-16 (MHD), and Omni Carbon (OC) valves. Results showed cavitation bubbles between 340 and 360 mu s after leaflet/housing impact of the MHS, MHD,, and OC valves, intensified by significant leaflet rebound. Squeeze flow, Venturi, and water hammer effects each contributed to cavitation, depending on valve design.
Date:	2008-03
Relation:	Asaio Journal. 2008 Mar-Apr;54(2):163-171.
Link to:	http://dx.doi.org/10.1097/MAT.0b013e3181641ae9
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1058-2916&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000259922700005
Cited Times(Scopus):	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=41349084409
Appears in Collections:	[Ned H. C. Hwang(2000-2008)] Conference Papers/Meeting Abstract

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