國家衛生研究院 NHRI:Item 3990099045/4577
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    题名: Squeeze flow measurements in mechanical heart valves
    作者: Lo, CW;Lu, PC;Liu, JS;Li, CP;Hwang, NH
    贡献者: Division of Medical Engineering Research
    摘要: High-speed squeeze flow during mechanical valve closure is often thought to cause cavitation, either between the leaflet tip and flat contact area in the valve housing, seating lip, or strut flat seat stop, depending on design. These sites have been difficult to measure within the housing, limiting earlier research to study of squeeze flow outside the housing or with computational fluid dynamics. We directly measured squeeze flow velocity with laser Doppler velocimetry at its site of occurrence within the St. Jude Medical (SJM), Omnicarbon (OC), and Medtronic Hall Standard (MHS) 29 mm valves in a mock circulation loop. Quartz glass provided an observation window to facilitate laser penetration. Our results showed increasing squeeze flow velocity at higher heart rates: 2.393.44 m/s for SJM, 3.07-4.33 m/s for OC, and 3.87-5.33 m/s for MHS. Strobe lighting technique captured the images of cavitation formation. Because these results were obtained in a mock circulation loop, one can assume this may occur in vivo resulting in valve damage, hemolysis, and thromboembolism. However, velocities of this magnitude alone cannot produce the pressure drop required for cavitation, and the applicability of the Bernoulli equation under these circumstances requires further investigation.
    日期: 2008-03
    關聯: Asaio Journal. 2008 Mar-Apr;54(2):156-162.
    Link to: http://dx.doi.org/10.1097/MAT.0b013e3181648da0
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1058-2916&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000259922700004
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=41349092122
    显示于类别:[黃煥常(2000-2008)] 會議論文/會議摘要

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