國家衛生研究院 NHRI:Item 3990099045/4541

NHRI > National Institute of Cancer Research > Ming Jacqueline Liu(1996-2007) > Periodical Articles > Item 3990099045/4541

Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/4541

Title:	Mitomycin-C induced hemolytic uremic syndrome: A case report and literature review
Authors:	Wu, DC;Liu, JM;Chen, YM;Yang, SL;Liu, SM;Chen, LT;WhangPeng, J
Contributors:	National Institute of Cancer Research
Abstract:	Hemolytic uremic syndrome spontaneously arises in a few patients with advanced cancer, but it is more commonly related to the use of certain chemotherapeutic agents. Mitomycin-C is, etiologically, the most common causative agent inducing hemolytic uremic syndrome, in a dose dependent manner, We report this syndrome, attributable to mitomycin-C at a cumulative dose of 40 mg/m(2), in a gastric cancer patient. A 42-year-old female with stage III gastric cancer underwent radical gastrectomy and was given mitomycin-C at 10 mg/m(2) intravenously every four weeks as adjuvant therapy, Hemolytic uremic syndrome was diagnosed three months after the last dose of mitomycin-C administration, The most prominent symptoms included pallor, hypertension and anasarca, with laboratory evidence of microangiopathic hemolytic anemia, azotemia and hyperkalemia, Her disease was progressive, but fortunately stabilized after staphylococcus column A dialysis, Her disease remained in remission for 24 months from the time of diagnosis, and then relapsed in the form of peritoneal carcinomatosis with partial intestinal obstruction.
Date:	1997-04
Relation:	Japanese Journal of Clinical Oncology. 1997 Apr;27(2):115-118.
Link to:	http://jjco.oxfordjournals.org/cgi/content/abstract/27/2/115
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0368-2811&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:A1997WX68200012
Cited Times(Scopus):	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0031113953
Appears in Collections:	[Ming Jacqueline Liu(1996-2007)] Periodical Articles [Jacqueline Whang-Peng(1996-2007)] Periodical Articles [Li-Tzong Chen] Periodical Articles

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