國家衛生研究院 NHRI:Item 3990099045/4539

NHRI > National Institute of Cancer Research > Ming Jacqueline Liu(1996-2007) > Periodical Articles > Item 3990099045/4539

Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/4539

Title:	Risk and patterns of brain metastases in colorectal cancer: 27-year experience
Authors:	Ko, F;Liu, J;Chen, W;Chiang, J;Lin, T;Lin, J
Contributors:	National Institute of Cancer Research
Abstract:	PURPOSE: In patients with colorectal cancer, brain metastasis is infrequent. This study aims to elucidate the risk, pattern of occurrence, and survival time after different treatment modalities. METHODS: A retrospective review of all patients with colorectal cancer admitted to the Veterans General Hospital-Taipei between 1970 and 1996 from our hospital was performed. Univariate analysis for survival determination was performed. RESULTS: Brain metastases developed subsequent to surgery for colorectal cancer in 53 well-documented patients, at a median of 36 months after surgery. Brain metastases were more commonly seen in rectal cancer and often occurred concurrently with lung metastases. Forty of these patients received active intervention in terms of surgery, chemotherapy, or radiotherapy, with surgical intervention achieving a significantly increased mean survival time (? standard deviation) compared with chemotherapy or radiotherapy or both of 86.6 ? 17.35 vs. 2.9 ? 0.59 months (P < 0.05). CONCLUSION: Increased awareness of the possibility of brain metastases, early diagnosis, and aggressive therapy can provide increased survival time for patients with colorectal cancer with brain metastases.
Date:	1999-11
Relation:	Diseases of the Colon and Rectum. 1999 Nov;42(11):1467-1471.
Link to:	http://dx.doi.org/10.1007/bf02235049
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0012-3706&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000083626900023
Cited Times(Scopus):	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0032713492
Appears in Collections:	[Ming Jacqueline Liu(1996-2007)] Periodical Articles

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