國家衛生研究院 NHRI:Item 3990099045/4537

NHRI > National Institute of Cancer Research > Ming Jacqueline Liu(1996-2007) > Periodical Articles > Item 3990099045/4537

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Title:	Prolonged survival in a nasopharyngeal carcinoma patient with multiple metastases: A case report and review of the literature
Authors:	Chou, CW;Liu, JM;Wu, MF;Li, AFY;Tie, CM;Chi, KH
Contributors:	National Institute of Cancer Research
Abstract:	Nasopharyngeal carcinoma is a common cancer in South East Asia, In the early stages, radiotherapy alone may achieve sustained control, but once metastasis occurs, it becomes an incurable disease with limited survival time, We report a case of nasopharyngeal carcinoma, initial stage T4NOMO, diagnosed in 1985 in a patient aged 36 years who received 70 Gy radiotherapy to the head and neck region, In 1988, relapse occurred with multiple lung metastases. The patient received many chemotherapy regimens with a very good response, including near complete remission with the first treatment regimen of cisplatin, 5-fluorouracil and leucovorin for lung metastases, and with the fifth chemotherapy regimen of ifosfamide as a single agent, After if osf amide treatment, there was residual fibrotic change in the lung and complete disappearance, lasting for almost a year, of the liver and bone lesions, The patient eventually died in July 1995 due to progressive disease. Prolonged survival after mainly thoracic metastasis is possible in patients with nasopharyngeal carcinoma, especially if the tumor is chemo-responsive.
Date:	1997-10
Relation:	Japanese Journal of Clinical Oncology. 1997 Oct;27(5):336-339.
Link to:	http://jjco.oxfordjournals.org/cgi/content/abstract/27/5/336
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0368-2811&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:A1997YG28200009
Cited Times(Scopus):	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0031254557
Appears in Collections:	[Ming Jacqueline Liu(1996-2007)] Periodical Articles

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