邻近类别 會議論文/會議摘要 [1/4] 專利 [0/11] 类别统计 近3年内发表的文件:0(0.00%) 含全文笔数:52(100.00%) 文件下载次数统计 下载大于0次:52(100.00%) 下载大于100次:52(100.00%) 全文下载总次数:41949(98.58%) 最后更新时间: 2024-12-01 06:53 上传排行 数据加载中..... 下载排行 数据加载中..... 最近上传 Probing for improved selectivity wi... EDEM2 and OS-9 are required for ER-... Fibroblast activation protein (FAP)... Role of HERP and a HERP-related pro... Derlin2 protein facilitates HRD1-me... Role of a propeller loop in the qua... Proline in transmembrane domain of ... Structure-activity relationship stu... Processing and turnover of the Hedg... Cleavage-site specificity of prolyl...

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日期	题名	關聯
2016-03	Probing for improved selectivity with dipeptide-derived inhibitors of dipeptidyl peptidases 8 and 9: The impact of P1-variation	MedChemComm. 2016 Mar;7(3):433-438.
2014-06-09	EDEM2 and OS-9 are required for ER-associated degradation of non-glycosylated sonic hedgehog	PLoS ONE. 2014 Jun 9;9(6):Article number e92164.
2014-02	Role of HERP and a HERP-related protein in HRD1-dependent protein degradation at the endoplasmic reticulum	Journal of Biological Chemistry. 2014 Feb 14;289 (7):4444-4454.
2014-02	Fibroblast activation protein (FAP) is essential for the migration of bone marrow mesenchymal stem cells through RhoA activation	PLoS ONE. 2014 Feb 13;9(2):Article number e88772.
2013-08	Derlin2 protein facilitates HRD1-mediated retro-translocation of sonic hedgehog at the endoplasmic reticulum	Journal of Biological Chemistry. 2013 Aug;288(35):25330-25339.
2011-11-04	Role of a propeller loop in the quaternary structure and enzymatic activity of prolyl dipeptidases DPP-IV and DPP9	FEBS Letters. 2011 Nov 4;585(21):3409-3414.
2011-09	Proline in transmembrane domain of type II protein DPP-IV governs Its translocation behavior through endoplasmic reticulum	Biochemistry. 2011 Sep;50(37):7909-7918.
2011-08	Structure-activity relationship studies on isoindoline inhibitors of dipeptidyl peptidases 8 and 9 (DPP8, DPP9): Is DPP8-selectivity an attainable goal?	Journal of Medicinal Chemistry. 2011 Aug;54(16):5737-5746.
2011-06	Cleavage-site specificity of prolyl endopeptidase FAP investigated with a full-length protein substrate	Journal of Biochemistry. 2011 Jun;149(6):685-692.
2011-03	Processing and turnover of the Hedgehog protein in the endoplasmic reticulum	Journal of Cell Biology. 2011 Mar;192(5):825-838.
2010-12	Downregulation of signaling-active IGF-1 by dipeptidyl peptidase IV (DPP-IV)	International Journal of Biomedical Science. 2010 Dec;6(4):301-309.
2010-10	Structural basis for the improved potency of peroxisome proliferator-activated receptor (PPAR) agonists	ChemMedChem. 2010 Oct;5(10):1707-1716.
2010-09	The dimeric transmembrane domain of prolyl dipeptidase DPP-IV contributes to its quaternary structure and enzymatic activities	Protein Science. 2010 Sep;19(9):1627-1638.
2010-08	Substituted 4-carboxymethylpyroglutamic acid diamides as potent and selective inhibitors of fibroblast activation protein	Journal of Medicinal Chemistry. 2010 Aug;53(18):6572-6583.
2010-06-15	(2S,4S)-1-[2-(1,1-Dimethyl-3-oxo-3-pyrrolidin-1-yl-propylamino)acetyl]-4-fluoro-pyrrolidine-2-carbonitrile: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV	Bioorganic and Medicinal Chemistry Letters. 2010 Jun 15;20(12):3596-3600.
2009-10	(1,3-Diphenyl-1H-pyrazol-4-yl)-methylamine analogues as inhibitors of dipeptidyl peptidases	Journal of the Chinese Chemical Society. 2009 Oct;56(5):1048-1055.
2009-09-03	Ankrd17, an ubiquitously expressed ankyrin factor, is essential for the vascular integrity during embryogenesis	FEBS Letters. 2009 Sep 3;583(17):2765-2771.
2009-07-15	Biochemistry, pharmacokinetics, and toxicology of a potent and selective DPP8/9 inhibitor	Biochemical Pharmacology. 2009 Jul 15;78(2):203-210.
2009-06	Enzyme Activity and Immunohistochemical Localization of Dipeptidyl Peptidase 8 and 9 in Male Reproductive Tissues	Journal of Histochemistry and Cytochemistry. 2009 Jun;57(6):531-541.
2009-06	A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitiors [Erratum: European Journal of Medicinal Chemistry. 2008 Aug;43(8):1603-1611.]	European Journal of Medicinal Chemistry. 2009 Jun;44(6):2763-2763.
2009-05-15	Biochemical properties and expression profile of human prolyl dipeptidase DPP9	Archives of Biochemistry and Biophysics. 2009 May 15;485(2):120-127.
2009-04-23	Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists	Journal of Medicinal Chemistry. 2009 Apr 23;52(8):2618-2622.
2009-04-01	Rational design and synthesis of potent and long-lasting glutamic acid-based dipeptidyl peptidase IV inhibitors	Bioorganic and Medicinal Chemistry Letters. 2009 Apr 1;19(7):1908-1912.
2009-03-15	Novel trans-2-aryl-cyclopropylamine analogues as potent and selective dipeptidyl peptidase IV inhibitors	Bioorganic and Medicinal Chemistry. 2009 Mar 15;17(6):2388-2399.
2009	Thiopurine analogue inhibitors of severe acute respiratory syndrome-coronavirus papain-like protease, a deubiquitinating and deISGylating enzyme	Antiviral Chemistry and Chemotherapy. 2009;19(4):151-156.

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