國家衛生研究院 NHRI:Item 3990099045/4415

NHRI > National Institute of Environmental Health Sciences > Ying-Chin Ko(2003-2009) > Periodical Articles > Item 3990099045/4415

Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/4415

Title:	Important prognostic factors for the long-term survival of subjects with primary liver cancer in Taiwan: A hyperendemic area
Authors:	Chen, PH;Lin, YC;Tu, HP;Chiang, SL;Ko, AMS;Hsu, CL;Chang, YF;Ko, YC
Contributors:	Division of Environmental Health and Occupational Medicine
Abstract:	This study used a large-scale cancer database in determining the survival prognostic factors among primary liver cancer (PLC) subjects. A total of 28,939 subjects diagnosed with PLC were analysed. Survival estimates were performed with Kaplan-Meier methods. Cox's proportional-hazards model estimated the death risk (hazard ratio (HR)) of prognostic factors. The prognostic indicators associated with higher risk of all-cause deaths are male gender (males versus females; HR = 1.16, 95% confidence intervals (CI), 1.13-1.20), diagnosis at later period (shown in 1990-1994 versus 1985-1989; HR = 1.04, 95% CI, 1.01-1.08), increasing age at diagnosis, subjects with adenocarcinoma/cholangiocarcinoma (CC) and with no therapy against those with chemotherapy The overall 5-year survival rate for all causes of death was significantly poorer in males (13.7%) than females (17.2%). Subjects diagnosed with hepatoblastoma and treated by surgical resection alone had superior prognosis. Particularly, subjects with adenocarcinoma and CC were more likely to die in other metastatic cancer.
Date:	2007-04
Relation:	European Journal of Cancer. 2007 Apr;43(6):1076-1084.
Link to:	http://dx.doi.org/10.1016/j.ejca.2007.01.022
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0959-8049&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000246120600021
Cited Times(Scopus):	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=33947596624
Appears in Collections:	[Ying-Chin Ko(2003-2009)] Periodical Articles

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