國家衛生研究院 NHRI:Item 3990099045/4318
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/4318


    Title: Comparison of efficacy and safety of exchange transfusion through different catheterizations: Femoral vein versus umbilical vein versus umbilical artery/vein
    Authors: Weng, YH;Chiu, YW
    Contributors: Division of Health Policy Research and Development
    Abstract: OBJECTIVE:: To compare the efficacy and safety of exchange transfusion (ET) via three different catheterization methods: femoral vein (FV); umbilical vein (UV); and umbilical artery/vein (UA/V). DESIGN:: A retrospective cohort of neonates who underwent ET for hyperbilirubinemia between 1996 and 2007 was surveyed. Subjects with gestational age <33 wks were excluded. SETTING:: Neonatal intensive care units in a tertiary referral hospital. PATIENTS:: A total of 109 neonates with 128 ET procedures (33 via FV, 35 via UV, and 60 via UA/V routes) were analyzed. MEASUREMENTS AND MAIN RESULTS:: There was no significant difference in the decline of total serum bilirubin between each group. When compared with the UA/V group, the transfusion rate was slower in the FV and UV groups (P < .001). Adverse events with clinical significance were more common in ET via the UA/V route than ET via the FV and UV routes (P < .05; odds ratio, 2.4; 95% confidence interval, 1.2-5.0). Neonates with ET via the UA/V route tended to have more asymptomatic laboratory aberrances (P < .01; odds ratio, 2.5; 95% confidence interval, 1.3-4.6). There were no significant differences in the transfusion rate (P = .498) and adverse events (P = .822) between the FV and UV groups. CONCLUSIONS:: ET through the FV route is an effective and secure method for the treatment of neonatal hyperbilirubinemia when the UV route is unavailable. Physicians should be cautious when using UA/V catheterization for ET.
    Date: 2011-01
    Relation: Pediatric Critical Care Medicine. 2011 Jan;12(1):61-64.
    Link to: http://dx.doi.org/10.1097/PCC.0b013e3181dbeb78
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1529-7535&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000285964500021
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=78751645775
    Appears in Collections:[Ya-Wen Chiu(2005-2013)] Periodical Articles

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