國家衛生研究院 NHRI:Item 3990099045/4314

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Title:	Surface deformation of gold nanorod-loaded poly(DL-lactide-co-glycolide) nanoparticles after near infrared irradiation: an active and controllable drug release system
Authors:	Chu, CH;Wang, YC;Tai, LA;Wu, LC;Yang, CS
Contributors:	Center for Nanomedicine Research
Abstract:	A novel drug release method for poly(DL-lactide-co-glycolide) (PLGA) nanoparticles is reported. NIR laser irradiation (808 +/- 3 nm) on gold nanorods (GNRs) co-encapsulated in PLGA nanoparticles triggered surface protuberances (as studied by AFM) and induced rapid drug release. The NIR thus acts as a non-invasive external light source for active and controllable drug release from the PLGA/GNR composite nanoparticles. This type of drug delivery system may be of value in in vivo target delivery in the future.
Date:	2010
Relation:	Journal of Materials Chemistry. 2010;20(16):3260-3264.
Link to:	http://dx.doi.org/10.1039/b925651m
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000276373500019
Cited Times(Scopus):	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=77950455652
Appears in Collections:	[Chung-Shi Yang] Periodical Articles

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