國家衛生研究院 NHRI:Item 3990099045/4257
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    題名: Vitamin D insufficiency and frailty syndrome in older adults living in a northern Taiwan community
    作者: Chang, CI;Chan, DC;Kuo, KN;Hsiung, CA;Chen, CY
    貢獻者: Division of Gerontology Research;Division of Biostatistics and Bioinformatics;Division of Health Policy Research and Development
    摘要: This study explored the association between vitamin D insufficiency and frailty syndrome defined by the Fried Frailty Index (FFI) and the Edmonton Frail Scale (EFS) in a northern Taiwan community. Data of 215 subjects participating in an integrated interventional trial involving community-dwelling older adults with a high frailty risk were analyzed. Subjects were first screened by telephone interview and then evaluated at a local hospital with questionnaires, physical performance tests, and serum 25(OH) D measurements. Of the 215 participants, 31% had 25(OH) D insufficiency (<20 ng/ml). Frail subjects based on the FFI were older, had lower Mini-Mental Status Exam (MMSE) scores, Barthel Index (BI) scores, and 25(OH) D levels. Using the EFS, frailer cases were more likely to be female, have less education, higher comorbid conditions, lower MMSE scores, lower Barthel Index scores, and lower 25(OH) D levels. The associations between insufficient 25(OH) D status and both frailty scales were significant. After adjustment of variables, the odds ratio of 25(OH) D insufficiency was 10.74 (95% CI 2.60-44.31) for frail versus robust individuals. The prevalence of vitamin D insufficiency was high in this population. There was a strong association between vitamin D insufficiency and the FFI. Vitamin D measurements and supplements are suggested for high-risk older people.
    日期: 2010-02
    關聯: Archives of Gerontology and Geriatrics. 2010 Feb;50(Suppl. 1):S17-S21.
    Link to: http://dx.doi.org/10.1016/S0167-4943(10)70006-6
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0167-4943&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000274865000005
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=77952538830
    顯示於類別:[熊昭] 期刊論文
    [陳慶餘(2006-2010)] 期刊論文
    [郭耿南(2003-2010)] 期刊論文

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