國家衛生研究院 NHRI:Item 3990099045/3358
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    题名: Important prognostic factors for the long-term survival of lung cancer subjects in Taiwan
    作者: Chiang, TA;Chen, PH;Wu, PF;Wang, TN;Chang, PY;Ko, AMS;Huang, MS;Ko, YC
    贡献者: Division of Environmental Health and Occupational Medicine
    摘要: Background: This study used a large-scale cancer database in determination of prognostic factors for the survival of lung cancer subjects in Taiwan. Methods: Total of 24,910 subjects diagnosed with lung cancer was analysed. Survival estimates by Kaplan-Meier methods. Cox proportional-hazards model estimated the death risk (hazard ratio (HR)) for various prognostic factors. Results: The prognostic indicators associated with a higher risk of lung cancer deaths are male gender (males versus females; HR = 1.07, 95% confidence intervals (CI): 1.03-1.11), males diagnosed in later periods (shown in 1991-1994 versus 1987-1990; HR = 1.13), older age at diagnosis, large cell carcinoma (LCC)/small cell carcinoma (SCC), and supportive care therapy over chemotherapy. The overall 5-year survival rate for lung cancer death was significantly poorer for males (21.3%) than females (23.6%). Subjects with squamous cell carcinoma (SQCC) and treatment by surgical resection alone had better prognosis. We find surgical resections to markedly increase 5-year survival rate from LCC, decreased risk of death from LCC, and no improved survival from SCC. Conclusion: Gender and clinical characteristics (i.e. diagnostic period, diagnostic age, histological type and treatment modality) play important roles in determining lung cancer survival. 穢 2008 Chiang et al; licensee BioMed Central Ltd.
    日期: 2008-11-07
    關聯: BMC Cancer. 2008 Nov 7;8:Article number 324.
    Link to: http://dx.doi.org/10.1186/1471-2407-8-324
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1471-2407&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000261556500001
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=57049146846
    显示于类别:[葛應欽(2003-2009)] 期刊論文

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