國家衛生研究院 NHRI:Item 3990099045/2704
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/2704


    Title: Satellite hole spectroscopy of thrombin-aptamer complexes
    Authors: Chang, TC;Lin, KC;Chiang, CC;Yang, YP;Chang, WS
    Contributors: National Institute of Cancer Research
    Abstract: he distinct nonresonant holes in the satellite hole spectra of a fluorescent dye molecule that is covalently attached to various oligonucleotides [d(G2T2G2TGTG2T2G2), d(G4T4G4), and d(CGCGT4CGCG); see schematic representation] in the presence of thrombin are indicators used to detect DNA–protein interactions. The results suggest that thrombin can potentially recognize quadruplex structures, but not a hairpin duplex oligonucleotide. p=5′-phosphate group, N=nucleotide.
    Keywords: Biochemistry & Molecular Biology;Chemistry, Medicinal
    Date: 2000-10-02
    Relation: Chembiochem. 2000 Oct;1(3):197-200.
    Link to: http://dx.doi.org/10.1002/1439-7633(20001002)1:3<197::AID-CBIC197>3.0.CO;2-I
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1439-4227&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000165767600005
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0034597444
    Appears in Collections:[Wun-Shaing Wayne Chang] Periodical Articles

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