國家衛生研究院 NHRI:Item 3990099045/2532

NHRI > National Institute of Environmental Health Sciences > Ying-Chin Ko(2003-2009) > Periodical Articles > Item 3990099045/2532

Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/2532

Title:	Prognostic factors associated with the survival of oral and pharyngeal carcinoma in Taiwan
Authors:	Chen, PH;Shieh, TY;Ho, PS;Tsai, CC;Yang, YH;Lin, YC;Ko, MS;Tsai, PC;Chiang, SL;Tu, HP;Ko, YC
Contributors:	Division of Environmental Health and Occupational Medicine
Abstract:	Background: In Taiwan, a distinct ethnic group variation in incidence and mortality rates has been suggested for most carcinomas. Our aim is to identify the role of prognostic factors associated with the survival of oral and pharyngeal carcinoma in Taiwan. Methods: Taiwan Cancer Registry records of 9039 subjects diagnosed with oral and pharyngeal carcinoma were analyzed. The population was divided into three ethnic groups by residence, which were Taiwanese aborigines, Hakka and Hokkien communities. Five-year survival rates were estimated by Kaplan-Meier methods. Ethnic curves differed significantly by log-rank test; therefore separate models for Taiwanese aborigines, Hakka and Hokkien were carried out. The Cox multivariate proportional hazards model was used to examine the role of prognostic factors on ethnic survival. Results: The five-year survival rates of oral and pharyngeal carcinoma were significantly poorer for Hokkien community (53.9%) and Taiwanese aborigines community (58.1%) compared with Hakka community (60.5%). The adjusted hazard ratio of Taiwanese aborigines versus Hakka was 1.07 (95% CI, 0.86-1.33) for oral and pharyngeal carcinoma mortality, and 1.16 (95% CI, 1.01-1.33) for Hokkien versus Hakka. Males had significantly poor prognosis than females. Subjects with tongue and/or mouth carcinoma presented the worst prognosis, whereas lip carcinoma had the best prognosis. Subjects with verrucous carcinoma had better survival than squamous cell carcinoma. Prognosis was the worst in elderly subjects, and subjects who underwent surgery had the highest survival rate. Conclusion: Our study presented that predictive variables in oral and pharyngeal carcinoma survival have been: ethnic groups, period of diagnosis, gender, diagnostic age, anatomic site, morphologic type, and therapy.
Keywords:	Oncology
Date:	2007-06-15
Relation:	BMC Cancer. 2007 Jun;7:Article number 101.
Link to:	http://dx.doi.org/10.1186/1471-2407-7-101
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1471-2407&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000248566600001
Cited Times(Scopus):	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=34547438904
Appears in Collections:	[Ying-Chin Ko(2003-2009)] Periodical Articles

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