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Showing items 151-200 of 212. (5 Page(s) Totally) << < 1 2 3 4 5 > >> View [10|25|50] records per page

Date	Title	Relation
2010-06-15	Fast-forwarding hit to lead: Aurora and epidermal growth factor receptor kinase inhibitor lead identification	Journal of Medicinal Chemistry. 2010 Jun 15;53(13):4980-4988.
2010-04-27	Oxadiazole compounds	US7705024B2/2010-04-27
2010-03-30	Pyrrolidine compounds	US7687504B2/2010-03-30
2010-03	Synthesis and biological activities of 2-Amino-1-arylidenamino imidazoles as orally active anticancer agents	Journal of Medicinal Chemistry. 2010 Mar;53(6):2409-2417.
2010-02-25	Anti-influenza drug discovery: structure-activity relationship and mechanistic insight into novel angelicin derivatives	Journal of Medicinal Chemistry. 2010 Feb 25;53(4):1519-1533.
2010-02-23	Pyrazole compound BPR1P0034 with potent and selective anti-influenza virus activity	Journal of Biomedical Science. 2010 Feb 23;17:Article number 13.
2010-02-01	Identification, SAR studies, and X-ray Co-crystallographic analysis of a novel furanopyrimidine aurora kinase a inhibitor	ChemMedChem. 2010 Feb 1;5(2):255-267.
2010-02	Antitumor activities and pharmacokinetics of silatecans DB-67 and DB-91	Pharmacological Research. 2010 Feb;61(2):108-115.
2010-01	BPR2-D2 targeting viral ribonucleoprotein complex-associated function inhibits oseltamivir-resistant influenza viruses	Journal of Antimicrobial Chemotherapy. 2010 Jan;65(1):63-71.
2009-11-01	Design and efficient synthesis of novel arylthiourea derivatives as potent hepatitis C virus inhibitors	Bioorganic and Medicinal Chemistry Letters. 2009 Nov 1;19(21):6063-6068.
2009-10	(1,3-Diphenyl-1H-pyrazol-4-yl)-methylamine analogues as inhibitors of dipeptidyl peptidases	Journal of the Chinese Chemical Society. 2009 Oct;56(5):1048-1055.
2009-09	Fast-forwarding kinase drug discovery: aurora and EGFR kinase inhibitor lead development	EJC Supplements. 2009 Sep;7(2):96.
2009-08-14	Tylophorine arrests carcinoma cells at G1 phase by downregulating cyclin A2 expression	Biochemical and Biophysical Research Communications. 2009 Aug 14;386(1):140-145.
2009-08-01	Design and synthesis of indole, 2,3-dihydro-indole, and 3,4-dihydro-2H-quinoline-1-carbothioic acid amide derivatives as novel HCV inhibitors	Bioorganic and Medicinal Chemistry Letters. 2009 Aug 1;19(15):4134-4138.
2009-07-23	Discovery of 2-[5-(4-chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydro-imidazol-4-thione (BPR-890) via an active metabolite. A novel, potent and selective cannabinoid-1 receptor inverse agonist with high antiobesity efficacy in DIO mice	Journal of Medicinal Chemistry. 2009 Jul 23;52(14):4496-4510.
2009-07-23	Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity	Journal of Medicinal Chemistry. 2009 Jul 23;52(14):4221-4233.
2009-07-15	Biochemistry, pharmacokinetics, and toxicology of a potent and selective DPP8/9 inhibitor	Biochemical Pharmacology. 2009 Jul 15;78(2):203-210.
2009-06-09	Treatment of coronavirus infection	US7544712B1/2009-06-09
2009-06	A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitiors [Erratum: European Journal of Medicinal Chemistry. 2008 Aug;43(8):1603-1611.]	European Journal of Medicinal Chemistry. 2009 Jun;44(6):2763-2763.
2009-04-23	Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists	Journal of Medicinal Chemistry. 2009 Apr 23;52(8):2618-2622.
2009-04-01	Design, synthesis, and anti-HCV activity of thiourea compounds	Bioorganic and Medicinal Chemistry Letters. 2009 Apr 1;19(7):1950-1955.
2009-04-01	Rational design and synthesis of potent and long-lasting glutamic acid-based dipeptidyl peptidase IV inhibitors	Bioorganic and Medicinal Chemistry Letters. 2009 Apr 1;19(7):1908-1912.
2009-03-15	Novel trans-2-aryl-cyclopropylamine analogues as potent and selective dipeptidyl peptidase IV inhibitors	Bioorganic and Medicinal Chemistry. 2009 Mar 15;17(6):2388-2399.
2009-02-26	Structure-based drug design of novel aurora kinase a inhibitors: Structural basis for potency and specificity	Journal of Medicinal Chemistry. 2009 Feb 26;52(4):1050-1062.
2009-02	Aurintricarboxylic acid inhibits influenza virus neuraminidase	Antiviral Research. 2009 Feb;81(2):123-131.
2009-01-22	Pyrrolidine compounds	AU2005221678/2009-01-22
2008-12-11	吲哚化合物	I304066/2008-12-11
2008-11-25	Anti-tumor compounds	US7456289B2/2008-11-25
2008-11-11	Indole compounds	US7449478B2/2008-11-11
2008-10-15	Analogues of 2-phenyl-ethenesulfonic acid phenyl ester have dual functions of inhibiting expression of inducible nitric oxide synthase and activating peroxisome proliferator-activated receptor gamma	Bioorganic and Medicinal Chemistry Letters. 2008 Oct 15;18(20):5676-5679.
2008-09-21	Bioisosteric replacement of the pyrazole 3-carboxamide moiety of rimonabant. A novel series of oxadiazoles as CB1 cannabinoid receptor antagonists	Organic and Biomolecular Chemistry. 2008 Sep 21;6(18):3399-3407.
2008-09-16	Pyrrolidine compounds	US7425633B2/2008-09-16
2008-09-11	Bioisosteric replacement of the pyrazole 5-aryl moiety of N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A). A novel series of alkynylthiophenes as potent and selective cannabinoid-1 receptor antagonists	Journal of Medicinal Chemistry. 2008 Sep 11;51(17):5397-5412.
2008-08	A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitors	European Journal of Medicinal Chemistry. 2008 Aug;43(8):1603-1611.
2008-07-21	吡咯啉啶化合物	I299039/2008-07-21
2008-07-09	Enhanced oral bioavailability of paclitaxel by D-alpha-tocopheryl polyethylene glycol 400 succinate in mice	International Journal of Pharmaceutics. 2008 Jul;359(1-2):174-181.
2008-07-01	Pyrrolidine compounds	KR10-0844593/2008-07-01
2008-06-01	A cell-based high-throughput screen for epidermal growth factor receptor pathway inhibitors	Analytical Biochemistry. 2008 Jun;377(1):89-94.
2008-05-01	抗腫瘤化合物	I296195/2008-05-01
2008-05	Bioassay-guided purification and identification of PPARa/gamma agonists from Chlorella sorokiniana	Phytotherapy Research. 2008 May;22(5):605-613.
2008-04-01	A mammalian cell-based reverse two-hybrid system for functional analysis of 3C viral protease of human enterovirus 71	Analytical Biochemistry. 2008 Apr;375(1):115-123.
2008-03-01	Aurora kinase A inhibitors: Identification, SAR exploration and molecular modeling of 6,7-dihydro-4H-pyrazolo-[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione scaffold	Bioorganic and Medicinal Chemistry Letters. 2008 Mar;18(5):1623-1627.
2008-02-07	Design, synthesis, and biological evaluation of novel alkenylthiophenes as potent and selective CB1 cannabinoid receptor antagonists	Organic and Biomolecular Chemistry. 2008 Feb;6(3):447-450.
2007-11	Novel small-molecule inhibitors of transmissible gastroenteritis virus	Antimicrobial Agents and Chemotherapy. 2007 Nov;51(11):3924-3931.
2007-10-01	Rapid and sensitive determination of fentanyl in dog plasma by on-line solid-phase extraction integrated with a hydrophilic column coupled to tandem mass spectrometry	Journal of Chromatography B. 2007 Oct;857(2):195-201.
2007-07	Biotransformation of 6-methoxy-3-(3 ',4 ',5 '-trimethoxy-benzoyl)-1-hindole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes	Drug Metabolism and Disposition. 2007 Jul;35(7):1042-1049.
2007-07	Anti-influenza drug discovery	Drugs of the Future. 2007 Jul;32(Suppl. A):97.
2007-04-18	Identification of novel small-molecule inhibitors of transmissible gastroenteritis virus	FASEB Journal. 2007 Apr 18;21(6):LB10.
2007-03-01	3-[2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-3-methyl-butyramide analogues as selective DPP-IV inhibitors for the treatment of type-II diabetes	Bioorganic and Medicinal Chemistry Letters. 2007 Mar;17(5):1274-1279.
2007-02-01	Development and validation of a liquid chromatography-tandem mass spectrometry for the determination of BPR0L075, a novel antimicrotuble agent, in rat plasma: Application to a pharmacokinetic study	Journal of Chromatography B. 2007 Feb;846(1-2):162-168.

Showing items 151-200 of 212. (5 Page(s) Totally) << < 1 2 3 4 5 > >> View [10|25|50] records per page