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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/1919


    Title: Correlates of antibiotic use in Taiwan hospitals
    Authors: McDonald, LC;Yu, HT;Yin, HC;Hsiung, CA;Hung, CC;Ho, M
    Contributors: Division of Clinical Research;Division of Biostatistics and Bioinformatics
    Abstract: OBJECTIVE: To determine factors that correlate with increased antibiotic use among adult inpatients in Taiwan. DESIGN: Retrospective survey of medical records. SETTING: 14 acute-care hospitals (8 regional hospitals, 6 medical centers) in Taiwan. PARTICIPANTS: A systematic probability sample from each hospital, totaling 663 adult inpatients who were discharged or had died in early 1999. MEASUREMENTS: Infectious disease physicians at the 14 hospitals collected data from medical records regarding patient demographics, hospitalization, discharge diagnosis, and antibiotics received. RESULTS: A total of 447 (67%) patients received antibiotics for an overall rate of 813 antibiotic-days (number of days patients received each antibiotic)/1,000 patient-days. Both the proportion of beds in intensive care units ([ICUs] Pearson correlation coefficient [r], 0.67; 95% confidence interval [CI95], 0.36-0.89; P < .01) and the proportion of patients admitted to surgical services (r, 0.66; CI95, 0.20-0.88; P=.01) correlated with the mean patient rate of antibiotic-days/hospital-day (MPAUD). In contrast, we found no correlation between the proportion of patients who received antibiotics and the MPAUD. Using multiple linear regression, medical center status wash the only independent predictor for increased MPAUD, (regression coefficient [b], 0.15; CI95, 0.05-0.24; P < .01). There was no correlation between pooled rates of antibiotic-days/hospital-day and any hospital demographic factors. First-generation cephalosporin (39%) and aminoglycoside (24%) use accounted for the majority of antibiotic-days. CONCLUSIONS: Antibiotic use is greater in medical centers than in regional hospitals and appears to be independent of surgical case mix or the proportion of ICU beds. Determination of multiple, independent measures of antibiotic use may be necessary to understand the relation between antibiotic use and resistance in hospitals.
    Keywords: Public, Environmental & Occupational Health;Infectious Diseases
    Date: 2001-09
    Relation: Infection Control and Hospital Epidemiology. 2001 Sep;22(9):565-571.
    Link to: http://dx.doi.org/10.1086/501953
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0899-823X&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000172230300007
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0035204277
    Appears in Collections:[何曼德(1997-2002)] 期刊論文
    [熊昭] 期刊論文
    [McDonald LC(1998-2000)] 期刊論文

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