Collection Patents [0/32] Periodical Articles [143/144] Conference Papers/Meeting Abstract [27/39] Siblings Su-Ying Wu [52/65] Others [58/60] Kak-Shan Shia [76/98] Yueh Andrew Yueh [29/32] Chung-Ming Chang [7/9] Jang-Yang Chang [18/18] Chun-Ping Chang [21/26] Shiow-Ju Lee [75/105] Jinq-Chyi Lee [23/24] Shu-Yu Lin [19/20] Ming-Shiu Hung [31/40] Shiow-Lin Pan(2009-2013) [16/17] Wen-Chieh Wang [13/15] Hung-Jung Wang [7/7] Chuan Shih(2014-2017) [35/39] Chun-Wei Tung [23/23] Ya-Hui Chi [21/25] Shau-Hua Ueng [22/24] Hong Zhuang [1/1] Shiu-Hwa Yeh [24/25] Teng-Kuang Yeh [133/152] Weir-Torn Jiaang [41/66] Hsing-Pang Hsieh [171/231] Yu-Sheng Chao(2002-2013) [120/212] Ching-Chuan Kuo [49/55] Lun Kelvin Tsou [28/29] Jyh-Haur Chern [31/52] Xin Chen(2002-2015) [53/67] Chiung-Tong Chen [180/212] Wan-Ching Yen [6/7] Ming-Chu Hsu(1997-2001) [3/10] Shu-Jung Chen(1998-2001) [3/11] Hua-Chien Chen(1997-2001) [9/9] Community Statistics Item counts issued in 3 years:9(4.19%) Items With Fulltext:170(79.07%) Download counts of the item Download times greater than 0:170(100.00%) Download times greater than 100:168(98.82%) Total Bitstream Download Counts:103418(1.93%) Last Update: 2024-12-01 13:37 Top Upload Loading... Top Download Loading... Recent Submissions Development of a humanized antibody... Reducing brain Abeta burden amelior... Discovery of novel AXL and MER inhi... Development of furanopyrimidine-bas... Targeting the phosphatidylserine-im... Synthesis and evaluation of small m... Extracellular HSP90alpha induces My... The beneficial effects of combining... Acyl-coenzyme a synthetase long-cha... Colloidal assemblies composed of po...

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Showing items 1-50 of 215. (5 Page(s) Totally) 1 2 3 4 5 > >> View [10|25|50] records per page

Date	Title	Relation
2024-07-04	Development of a humanized antibody targeting extracellular HSP90alpha to suppress endothelial-mesenchymal transition-enhanced tumor growth of pancreatic adenocarcinoma cells	Cells. 2024 Jul 04;13(13):Article number 1146.
2024-04	Reducing brain Abeta burden ameliorates high-fat diet-induced fatty liver disease in APP/PS1 mice	Biomedicine and Pharmacotherapy. 2024 Apr;173:Article number 116404.
2023-10	Discovery of novel AXL and MER inhibitors as potential anticancer and immune modulator drugs	Annals of Oncology. 2023 Oct;34(Suppl. 2):S214.
2023-02-07	Development of furanopyrimidine-based orally active third-generation EGFR inhibitors for the treatment of non-small cell lung cancer	Journal of Medicinal Chemistry. 2023 Feb 7;66(4):2566-2588.
2022-10-13	Targeting the phosphatidylserine-immune checkpoint with a small-molecule maytansinoid conjugate	Journal of Medicinal Chemistry. 2022 Oct 13;65(19):12802-12824.
2022-06-21	Synthesis and evaluation of small molecule drug conjugates harnessing thioester-linked maytansinoids	Pharmaceutics. 2022 Jun 21;14(7):Article number 1316.
2022-01-18	Acyl-coenzyme a synthetase long-chain family member 4 is involved in viral replication organelle formation and facilitates virus replication via ferroptosis	mBio. 2022 Jan 18;13(1):Article number e0271721.
2022-01-11	Extracellular HSP90alpha induces MyD88-IRAK complex-associated IKKalpha/Beta−NF-KappaB/IRF3 and JAK2/TYK2−STAT-3 signaling in macrophages for tumor-promoting M2-polarization	Cells. 2022 Jan 11;11(2):Article number 229.
2022-01-05	The beneficial effects of combining anti-Abeta antibody NP106 and curcumin analog TML-6 on the treatment of Alzheimer’s disease in APP/PS1 mice	International Journal of Molecular Sciences. 2022 Jan 5;23(1):Article number 556.
2021-07-30	The effects of Abeta1-42 binding to the SARS-CoV-2 spike protein S1 subunit and angiotensin-converting enzyme 2	International Journal of Molecular Sciences. 2021 Jul 30;22(15):Article number 8226.
2021-07-16	Colloidal assemblies composed of polymeric micellar/emulsified systems integrate cancer therapy combining a tumor-associated antigen vaccine and chemotherapeutic regimens	Nanomaterials. 2021 Jul 16;11(7):Article number 1844.
2021-01	Effect of a neuropilin-1-derived virus receptor trap on enterovirus A71 infection in vitro	Antimicrobial Agents and Chemotherapy. 2021 Jan;65(1):Article number e00695-20.
2020-12	Engineering a novel IgG-like bispecific antibody against enterovirus A71	Biochemistry and Biophysics Reports. 2020 Dec;24:Article number 100860.
2020-08-20	Discovery of M protease inhibitors encoded by SARS-CoV-2	Antimicrobial Agents and Chemotherapy. 2020 Aug 20;64(9):e00872-20.
2020-08	Artificial intelligence approach fighting COVID-19 with repurposing drugs	Biomedical Journal. 2020 Aug;43(4):355-362.
2020-08	Repurposing old drugs as antiviral agents for coronaviruses	Biomedical Journal. 2020 Aug;43(4):368-374.
2020-06-02	Zika virus NS3 protease pharmacophore anchor model and drug discovery	Scientific Reports. 2020 Jun 2;10:Article number 8929.
2020-05	Antiviral activity of llama-inspired single domain antibody against Enterovirus A71	Antimicrobial Agents and Chemotherapy. 2020 May;64(5):Article number e01922-19.
2020-05	Drug-like property optimization: Discovery of orally bioavailable quinazoline-based multi-targeted kinase inhibitors	Bioorganic Chemistry. 2020 May;98:Article number 103689.
2020-04	BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, produces potent antinociceptive effects with safer properties than morphine	Neuropharmacology. 2020 Apr;166:Article number 107678.
2019-11-27	Discovery of a furanopyrimidine-based epidermal growth factor receptor inhibitor (DBPR112) as a clinical candidate for the treatment of non-small cell lung cancer	Journal of Medicinal Chemistry. 2019 Nov 27;62(22):10108-10123.
2019-10	Discovery of clinical candidate DBPR112, a furanopyrimidine-based epidermal growth factor receptor inhibitor for the treatment of non-small cell lung cancer	Annals of Oncology. 2019 Oct;30(Suppl. 5):789.
2019-10	Inhibition of Rspo-Wnt pathway facilitates checkpoint blockade therapy by anti-RSPO3 antibody (DBPR117)	Annals of Oncology. 2019 Oct;30(Suppl. 5):191.
2019-07-11	Linker optimization and therapeutic evaluation of phosphatidylserine-targeting zinc dipicolylamine-based drug conjugates	Journal of Medicinal Chemistry. 2019 Jul 11;62(13):6047-6062.
2019-05-28	Identification of novel anti-liver cancer small molecules with better therapeutic index than sorafenib via zebrafish drug screening platform	Cancers. 2019 May 28;11(6):Article number 739.
2019-04-01	A novel, potent, and orally bioavailable thiazole HCV NS5A inhibitor for the treatment of hepatitis C virus	European Journal of Medicinal Chemistry. 2019 Apr 1;167:245-268.
2019-02-20	Convallatoxin enhance the ligand-induced mu-opioid receptor endocytosis and attenuate morphine antinociceptive tolerance in mice	Scientific Reports. 2019 Feb 20;9:Article number 2405.
2018-12	Dendritic cell-derived exosomes increase the efficacy of anti-PD-L1 antibody in melanoma model	Cancer Science. 2018 Dec;109(Suppl. 2):1322.
2018-12	Targeting RSPO3 reduces stem cell function in RSPO3-Fusion-positive colon cancer and RSPO3 high lung cancer	Cancer Science. 2018 Dec;109(SI, Suppl. 2):210.
2018-12	Targeting RSPO3 reduces stem cell function in RSPO3-Fusion-positive colon cancer and RSPO3 high lung cancer	Cancer Science. 2018 Dec;109(Suppl. 2, SI):1257.
2018-10	Identification of novel Cdc7 kinase inhibitors as anti-cancer agents that target the interaction with Dbf4 by the fragment complementation and drug repositioning approach	EBioMedicine. 2018 Oct;36:241-251.
2018-08-24	BPR1J373, a novel multitargeted kinase inhibitor, effectively suppresses the growth of gastrointestinal stromal tumor	Cancer Science. 2018 Nov;109(11):3591-3601.
2018-07	Clinical candidate DBPR112: A novel epidermal growth factor receptor inhibitor as a promising treatment for non-small cell lung cancer	Cancer Research. 2018 Jul;78(13, Suppl.):Meeting Abstract 4789.
2018-01-23	Identification of danthron as an isoform-specific inhibitor of HEME OXYGENASE-1/cytochrome P450 reductase interaction with anti-tumor activity	Journal of Biomedical Science. 2018 Jan 23;25:Article number 6.
2018-01	Discovery and development of DBPR112 as a clinical candidate: A novel EGFR inhibitor for non-small cell lung cancer	Cancer Science. 2018 Jan;109(Suppl. 1):739.
2017-09-26	Identification of neuraminidase inhibitors against dual H274Y/I222R mutant strains	Scientific Reports. 2017 Sep 26;7:Article number 12336.
2017-07	Targeting tumor associated phosphatidylserine with new zinc dipicolylamine-based drug conjugates	Bioconjugate Chemistry. 2017 Jul;28(7):1878-1892.
2017-04	Discovery of BPR1K871-a quinazoline based multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation	Abstracts of Papers of the American Chemical Society. 2017 Apr;253:Meeting Abstract 482.
2017-01	A potent, selective, and orally bioavailable HCV NS5A inhibitor for treatment of Hepatitis C Virus: (S)-1-((R)-2-(Cyclopropanecarboxamido)-2-phenylacetyl)-N-(4-phenylthiazo l-2-yl)pyrrolidine-2-carboxamide	Journal of Medicinal Chemistry. 2017 Jan;60(1):228-247.
2016-12	Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation	Oncotarget. 2016 Dec;7(52):86239-86256.
2016-12	Glucocorticoids may compromise the effect of gefitinib in non-small cell lung cancer	Oncotarget. 2016 Dec;7(52):85917-85928.
2016-12	Novel cKIT kinase inhibitor, BPRCKJ001, as an advanced therapeutic candidate for GIST	Annals of Oncology. 2016 Dec;27(Suppl. 9):Meeting Abstract 2P.
2016-11-29	Discovery of novel inhibitors of Aurora kinases with indazole scaffold: In silico fragment-based and knowledge-based drug design	European Journal of Medicinal Chemistry. 2016 Nov 29;124:186-199.
2016-10	BPR1J373, an oral multiple tyrosine kinase inhibitor, targets c-KIT for the treatment of c-KIT driven myeloid leukemia	Molecular Cancer Therapeutics. 2016 Oct;15(10):2323-2333.
2016-09	Mycotoxin patulin suppresses innate immune responses by mitochondrial dysfunction and p62/sequestosome-1-dependent mitophagy	Journal of Biological Chemistry. 2016 Sep;291(37):19299-19311.
2016-07-28	Design and synthesis of 1,2,3-triazole-containing N-acyl zanamivir analogs as potent neuraminidase inhibitors	European Journal of Medicinal Chemistry. 2016 Jul 28;123:397-406.
2016-05-19	Non-small-cell lung cancer cells combat epidermal growth factor receptor tyrosine kinase inhibition through immediate adhesion-related responses	OncoTargets and Therapy. 2016 May 19;9:2961-2973.
2016-02-26	Using mutagenesis to explore conserved residues in the RNA-binding groove of influenza A virus nucleoprotein for antiviral drug development	Scientific Reports. 2016 Feb 26;6:Article number 21662.
2016-01-01	Bispecific antibody conjugated manganese-based magnetic engineered iron oxide for imaging of HER2/neu- and EGFR-expressing tumors	Theranostics. 2016 Jan 1;6(1):118-130.
2015-10	Identification of substituted naphthotriazolediones as novel tryptophan 2,3-dioxygenase (TDO) inhibitors through structure-based virtual screening	Journal of Medicinal Chemistry. 2015 Oct;58 (19):7807-7819.

Showing items 1-50 of 215. (5 Page(s) Totally) 1 2 3 4 5 > >> View [10|25|50] records per page