國家衛生研究院 NHRI:Item 3990099045/1786
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/1786


    Title: Tests of equivalence and non-inferiority for diagnostic accuracy based on the paired areas under ROC curves
    Authors: Liu, JP;Ma, MC;Wu, CY;Tai, JY
    Contributors: Division of Biostatistics and Bioinformatics
    Abstract: Assessment of equivalence or non-inferiority in accuracy between two diagnostic procedures often involves comparisons of paired areas under the receiver operating characteristic (ROC) curves. With some pre-specified clinically meaningful limits, the current approach to evaluating equivalence is to perform the two one-sided tests (TOST) based on the difference in paired areas under ROC curves estimated by the non-parametric method. We propose to use the standardized difference for assessing equivalence or non-inferiority in diagnostic accuracy based on paired areas under ROC curves between two diagnostic procedures. The bootstrap technique is also suggested for both non-parametric method and the standardized difference approach. A simulation study was conducted empirically to investigate the size and power of the four methods for various combinations of distributions, data types, sample sizes, and different correlations. Simulation results demonstrate that the bootstrap procedure of the standardized difference approach not only can adequately control the type I error rate at the nominal level but also provides equivalent power under both symmetrical and skewed distributions. A numerical example using published data illustrates the proposed methods.
    Keywords: Mathematical & Computational Biology;Public, Environmental & Occupational Health;Medical Informatics;Medicine, Research & Experimental;Statistics & Probability
    Date: 2006-04-15
    Relation: Statistics in Medicine. 2006 Apr;25(7):1219-1238.
    Link to: http://dx.doi.org/10.1002/sim.2358
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0277-6715&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000236528500009
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=33645469682
    Appears in Collections:[Jen-Pei Liu(1998-2002)] Periodical Articles

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