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http://ir.nhri.org.tw/handle/3990099045/16471
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| Title: | Exposure distribution and profiles of paraben in Taiwanese (2013-2016) |
| Authors: | Chang, JW;Huang, YH;Lin, YJ;Chen, HC;Chang, WT;Huang, PC |
| Contributors: | National Institute of Environmental Health Sciences |
| Abstract: | Parabens are well-known endocrine disrupting chemicals (EDCs), which is added in food and pharmaceuticals and personal care products (PPCPs) as preservatives. Therefore, the aims of this study were: 1) to use the representative urine sample of the general Taiwan population and establish the background level of urinary parabens. We selected 1345 adults (ages 18-97 yrs) and 622 minors (ages 7-17 yrs) which was from a representative Survey from 2013 to 2016. The questionnaire, the morning blood sample and the first-morning urine sample were collected from the subjects and analyzed the urinary parabens from each participant including methylparaben (MeP), ethylparaben (EtP), propylparaben (PrP) and butylparaben (BuP) by using ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). We found the general Taiwanese were exposure at a high level of four parabens, especially MeP and PrP. The geometric mean (GM) of parabens for adults were higher than minors (adults: MeP, 395; EtP, 39.5; PrP, 103 and BuP 5.81 μg/L; minors: MeP, 288; EtP, 25.0; PrP, 65.4 and BuP 4.36 μg/L). The level of four parabens was higher than other countries. We concluded that paraben exposure of the general population in Taiwan varies by sex, age, and region. Exposure by the ≥18-year-old group to MeP, PrP, and BuP in Taiwan remains higher than that of adult from other countries. Reference values (RVs) of paraben in Taiwan were established in the current study. |
| Date: | 2024-06-07 |
| Relation: | 18th Conference of the International Society of Indoor Air Quality and Climate, INDOOR AIR 2024 - Conference Program and Proceedings. 2024 Jun 07-11:882-888. |
| Link to: | https://www.proceedings.com/content/076/076990webtoc.pdf |
| Cited Times(Scopus): | https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85210844006 |
| Appears in Collections: | [黃柏菁] 會議論文/會議摘要
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