國家衛生研究院 NHRI:
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    最後更新時間: 2024-12-01 13:09


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    日期題名關聯
    2024-10-29 DBPR116, a prodrug of BPRMU191, in combination with naltrexone as a safer opioid analgesic than morphine via peripheral administration Journal of Medicinal Chemistry. 2024 Oct 29;Article in Press.
    2024-07-17 Discovery of a mu-opioid receptor modulator that in combination with morphinan antagonists induces analgesia Cell Chemical Biology. 2024 Jul 17;Article in Press.
    2023-02-07 Development of furanopyrimidine-based orally active third-generation EGFR inhibitors for the treatment of non-small cell lung cancer Journal of Medicinal Chemistry. 2023 Feb 7;66(4):2566-2588.
    2022-11 Selective and antagonist-dependent µ-opioid receptor activation by the combination of 2-{[2-(6-chloro-3,4-dihydro-1(2H)-quinolinyl)-2-oxoethyl]sulfanyl}-5-phenyl-4,6-(1H,5H)-pyrimidinedione and naloxone/naltrexone Bioorganic Chemistry. 2022 Nov;128:Article number 105905.
    2021-07-16 Colloidal assemblies composed of polymeric micellar/emulsified systems integrate cancer therapy combining a tumor-associated antigen vaccine and chemotherapeutic regimens Nanomaterials. 2021 Jul 16;11(7):Article number 1844.
    2021-01 Overcoming vincristine resistance in cancer: Computational design and discovery of piperine-inspired P-glycoprotein inhibitors Chemical Biology and Drug Design. 2021 Jan;97(1):51-66.
    2020-08 Design of a potent anticancer lead inspired by natural products from traditional Indian medicine Journal of Biomolecular Structure and Dynamics. 2020 Aug;38(12):3563-3577.
    2020-05 Drug-like property optimization: Discovery of orally bioavailable quinazoline-based multi-targeted kinase inhibitors Bioorganic Chemistry. 2020 May;98:Article number 103689.
    2020-01 Identification of novel quinoline inhibitor for EHMT2/G9a through virtual screening Biochimie. 2020 Jan;168:220-230.
    2019-12 Lysosomal cysteine protease cathepsin S is involved in cancer cell motility by regulating store-operated Ca(2+) entry Biochimica et Biophysica Acta. Molecular Cell Research. 2019 Dec;1866(12):Article number 118517.

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