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2024-10-29
DBPR116, a prodrug of BPRMU191, in combination with naltrexone as a safer opioid analgesic than morphine via peripheral administration
Journal of Medicinal Chemistry. 2024 Oct 29;Article in Press.
2024-07-17
Discovery of a mu-opioid receptor modulator that in combination with morphinan antagonists induces analgesia
Cell Chemical Biology. 2024 Jul 17;Article in Press.
2023-02-07
Development of furanopyrimidine-based orally active third-generation EGFR inhibitors for the treatment of non-small cell lung cancer
Journal of Medicinal Chemistry. 2023 Feb 7;66(4):2566-2588.
2022-11
Selective and antagonist-dependent µ-opioid receptor activation by the combination of 2-{[2-(6-chloro-3,4-dihydro-1(2H)-quinolinyl)-2-oxoethyl]sulfanyl}-5-phenyl-4,6-(1H,5H)-pyrimidinedione and naloxone/naltrexone
Bioorganic Chemistry. 2022 Nov;128:Article number 105905.
2021-07-16
Colloidal assemblies composed of polymeric micellar/emulsified systems integrate cancer therapy combining a tumor-associated antigen vaccine and chemotherapeutic regimens
Nanomaterials. 2021 Jul 16;11(7):Article number 1844.
2021-01
Overcoming vincristine resistance in cancer: Computational design and discovery of piperine-inspired P-glycoprotein inhibitors
Chemical Biology and Drug Design. 2021 Jan;97(1):51-66.
2020-08
Design of a potent anticancer lead inspired by natural products from traditional Indian medicine
Journal of Biomolecular Structure and Dynamics. 2020 Aug;38(12):3563-3577.
2020-05
Drug-like property optimization: Discovery of orally bioavailable quinazoline-based multi-targeted kinase inhibitors
Bioorganic Chemistry. 2020 May;98:Article number 103689.
2020-01
Identification of novel quinoline inhibitor for EHMT2/G9a through virtual screening
Biochimie. 2020 Jan;168:220-230.
2019-12
Lysosomal cysteine protease cathepsin S is involved in cancer cell motility by regulating store-operated Ca(2+) entry
Biochimica et Biophysica Acta. Molecular Cell Research. 2019 Dec;1866(12):Article number 118517.
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