國家衛生研究院 NHRI:Item 3990099045/15973
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    题名: Association between wet-bulb globe temperature and kidney function in different geographic regions in a large Taiwanese population study
    作者: Su, WY;Wu, PH;Lin, MY;Wu, PY;Tsai, YC;Chiu, YW;Chang, JM;Hung, CH;Wu, CD;Kuo, CH;Chen, SC
    贡献者: National Institute of Environmental Health Sciences
    摘要: The worldwide prevalence and incidence rates of end-stage renal disease have been increasing, and the trend is pronounced in Taiwan. This is especially evident in southern Taiwan, where the wet-bulb globe temperature (WBGT) is consistently higher than in other regions. The association between kidney function and WBGT has not been fully investigated. Therefore, the aim of this study was to evaluate the association between estimated glomerular filtration rate (eGFR) and WBGT and variations in this association across different geographic regions in Taiwan. We used the Taiwan Biobank (TWB) to obtain data on community-dwelling individuals, linked these data with WBGT data obtained from the Central Weather Bureau and then processed the data using a machine learning model. WBGT data were recorded during the working period of the day from 8:00 a.m. to 5:00 p.m. These data were then compiled as 1-year, 3-year and 5-year averages, recorded prior to the survey year of the TWB of each participant. We identified 114 483 participants who had WBGT data during 2012-2020. Multivariable analysis showed that, in northern Taiwan, increases in 1- and 3-year averages of WBGT during the working period (beta = -0.092, P = .043 and beta = -0.193, P < .001, respectively) were significantly associated with low eGFR. In southern Taiwan, increases in 1-, 3- and 5-year averages of WBGT during the working period (beta = -0.518, P < .001; beta = -0.690, P < .001; and beta = -0.386, P = .001, respectively) were gnificantly associated with low eGFR. These findings highlight the importance of heat protection for people working outdoors or in high-temperature environments as a measure to prevent negative impacts on kidney function. Moreover, we observed that in southern Taiwan, every 1 degrees C increase in WBGT had a greater impact on the decrease in eGFR compared with other regions in Taiwan.
    日期: 2024-07-12
    關聯: Clinical Kidney Journal. 2024 Jul 12;17(7):Article number sfae173.
    Link to: http://dx.doi.org/10.1093/ckj/sfae173
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=2048-8505&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:001269778500002
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85198713668
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