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http://ir.nhri.org.tw/handle/3990099045/15880
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| Title: | Global and regional cardiovascular mortality attributable to nonoptimal temperatures over time |
| Authors: | Hundessa, S;Huang, W;Zhao, Q;Wu, Y;Wen, B;Alahmad, B;Armstrong, B;Gasparrini, A;Sera, F;Tong, S;Madureira, J;Kyselý, J;Schwartz, J;Vicedo-Cabrera, AM;Hales, S;Johnson, A;Li, S;Guo, Y;Jaakkola, JJK;Ryti, N;Urban, A;Tobias, A;Royé, D;Lavigne, E;Ragettli, MS;Åström, C;Raz, R;Pascal, M;Kan, H;Goodman, P;Zeka, A;Hashizume, M;Diaz, MH;Seposo, X;Nunes, B;Kim, H;Lee, W;Íñiguez, C;Guo, YL;Pan, SC;Zanobetti, A;Dang, TN;Van Dung, D;Schneider, A;Entezari, A;Analitis, A;Forsberg, B;Ameling, C;Houthuijs, D;Indermitte, E;Mayvaneh, F;Acquaotta, F;de'Donato, F;Carrasco-Escobar, G;Orru, H;Katsouyanni, K;de Sousa Zanotti Stagliorio Coelho, M;Ortega, NV;Scovronick, N;Michelozzi, P;Correa, PM;Nascimento Saldiva, PH;Abrutzky, R;Osorio, S;Colistro, V;Huber, V;Honda, Y;Kim, Y;Bell, M;Xu, R;Yang, Z;Roradeh, H;Félix Arellano, EE;Rao, S;Carlos Chua, PL;da Silva, SDNP;De la Cruz Valencia, C |
| Contributors: | National Institute of Environmental Health Sciences |
| Abstract: | Background: The association between nonoptimal temperatures and cardiovascular mortality risk is recognized. However, a comprehensive global assessment of this burden is lacking. Objectives: The goal of this study was to assess global cardiovascular mortality burden attributable to nonoptimal temperatures and investigate spatiotemporal trends. Methods: Using daily cardiovascular deaths and temperature data from 32 countries, a 3-stage analytical approach was applied. First, location-specific temperature–mortality associations were estimated, considering nonlinearity and delayed effects. Second, a multivariate meta-regression model was developed between location-specific effect estimates and 5 meta-predictors. Third, cardiovascular deaths associated with nonoptimal, cold, and hot temperatures for each global grid (55 km × 55 km resolution) were estimated, and temporal trends from 2000 to 2019 were explored. Results: Globally, 1,801,513 (95% empirical CI: 1,526,632-2,202,831) annual cardiovascular deaths were associated with nonoptimal temperatures, constituting 8.86% (95% empirical CI: 7.51%-12.32%) of total cardiovascular mortality corresponding to 26 deaths per 100,000 population. Cold-related deaths accounted for 8.20% (95% empirical CI: 6.74%-11.57%), whereas heat-related deaths accounted for 0.66% (95% empirical CI: 0.49%-0.98%). The mortality burden varied significantly across regions, with the highest excess mortality rates observed in Central Asia and Eastern Europe. From 2000 to 2019, cold-related excess death ratios decreased, while heat-related ratios increased, resulting in an overall decline in temperature-related deaths. Southeastern Asia, Sub-Saharan Africa, and Oceania observed the greatest reduction, while Southern Asia experienced an increase. The Americas and several regions in Asia and Europe displayed fluctuating temporal patterns. Conclusions: Nonoptimal temperatures substantially contribute to cardiovascular mortality, with heterogeneous spatiotemporal patterns. Effective mitigation and adaptation strategies are crucial, especially given the increasing heat-related cardiovascular deaths amid climate change. |
| Date: | 2024-06-11 |
| Relation: | Journal of the American College of Cardiology. 2024 Jun 11;83(23):2276-2287. |
| Link to: | http://dx.doi.org/10.1016/j.jacc.2024.03.425 |
| JIF/Ranking 2023: | http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0735-1097&DestApp=IC2JCR |
| Cited Times(Scopus): | https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85194106563 |
| Appears in Collections: | [郭育良] 期刊論文
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| SCP85194106563.pdf | 2536Kb | Adobe PDF | 65 | View/Open |
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