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Please use this identifier to cite or link to this item:
http://ir.nhri.org.tw/handle/3990099045/15863
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| Title: | Innovative technologies for the fabrication of 3D/4D smart hydrogels and its biomedical applications - A comprehensive review |
| Authors: | Shashikumar, U;Saraswat, A;Deshmukh, K;Hussain, CM;Chandra, P;Tsai, PC;Huang, PC;Chen, YH;Ke, LY;Lin, YC;Chawla, S;Ponnusamy, VK |
| Contributors: | National Institute of Environmental Health Sciences |
| Abstract: | Repairing and regenerating damaged tissues or organs, and restoring their functioning has been the ultimate aim of medical innovations. 'Reviving healthcare' blends tissue engineering with alternative techniques such as hydrogels, which have emerged as vital tools in modern medicine. Additive manufacturing (AM) is a practical manufacturing revolution that uses building strategies like molding as a viable solution for precise hydrogel manufacturing. Recent advances in this technology have led to the successful manufacturing of hydrogels with enhanced reproducibility, accuracy, precision, and ease of fabrication. Hydrogels continue to metamorphose as the vital compatible bio-ink matrix for AM. AM hydrogels have paved the way for complex 3D/4D hydrogels that can be loaded with drugs or cells. Bio-mimicking 3D cell cultures designed via hydrogel-based AM is a groundbreaking in-vivo assessment tool in biomedical trials. This brief review focuses on preparations and applications of additively manufactured hydrogels in the biomedical spectrum, such as targeted drug delivery, 3D-cell culture, numerous regenerative strategies, biosensing, bioprinting, and cancer therapies. Prevalent AM techniques like extrusion, inkjet, digital light processing, and stereo-lithography have been explored with their setup and methodology to yield functional hydrogels. The perspectives, limitations, and the possible prospects of AM hydrogels have been critically examined in this study. |
| Date: | 2024-06 |
| Relation: | Advances in Colloid and Interface Science. 2024 Jun;328:Article number 103163. |
| Link to: | http://dx.doi.org/10.1016/j.cis.2024.103163 |
| JIF/Ranking 2023: | http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0001-8686&DestApp=IC2JCR |
| Cited Times(WOS): | https://www.webofscience.com/wos/woscc/full-record/WOS:001241312000001 |
| Cited Times(Scopus): | https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85192792764 |
| Appears in Collections: | [黃柏菁] 期刊論文
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Size | Format | |
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| PUB38749384.pdf | | 8102Kb | Adobe PDF | 83 | View/Open |
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