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http://ir.nhri.org.tw/handle/3990099045/15720
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| Title: | Food-induced anaphylaxis among adults and children: A Taiwan tertiary hospital experience from 2001 to 2020 |
| Authors: | Gau, CC;Yeh, YH;Lee, HJ;Chuang, YY;Juan, YT;Huang, HY;Tsai, HJ;Yao, TC |
| Contributors: | Institute of Population Health Sciences |
| Abstract: | Background: Little is known regarding food-induced-anaphylaxis in Asia. We aimed to investigate the clinical characteristics of food-induced-anaphylaxis in adults as compared to children in terms of triggers, clinical features, and treatments. Method: We conducted an observational and descriptive study of all anaphylaxis patients in Chang Gung Memorial Hospital, the largest tertiary hospital in Taiwan, from 2001 to 2020. Cases were considered anaphylaxis based on National Institute of Allergy and Infectious Diseases/Food Allergy and Anaphylaxis Network criteria. Data on triggers, clinical features, and treatments of food-induced-anaphylaxis was recorded and compared between adults and children (<18 years). Results: We identified 287 food-induced anaphylaxis episodes over a 20-year period, with 182 (63.4%) occurred in adults. The top 3 common triggers of food-induced anaphylaxis in adults were seafood (52.8%), fruit (9.3%), and wheat (3.9%), while the top 3 common triggers in children were seafood (37.1%), egg (18.1%), and cow's milk (7.6%). The most frequent clinical manifestations were mucocutaneous symptoms (98.4% in adults vs. 98.1% in children, p = 0.87), followed by respiratory symptoms (79.1% in adults vs. 83.8% in children, p = 0.33). Cardiovascular (79.7% in adults vs. 48.6% in children, p < 0.01) and neurological symptoms (44.0% vs. 27.6%, p = 0.01) are more common in adults than in children. Epinephrine was administered in 61.3% of adults and 57.7% of children (p = 0.55). Regarding other treatments, adults were more likely than children to receive antihistamines (95.0% vs. 82.7%, p < 0.01), corticosteroids (86.2% vs. 70.2%, p < 0.01), and inotropes (3.9% vs. 0%, p = 0.04). Conclusion: This study in Asia demonstrates that seafood, fruit, and wheat were the most common triggers of food-induced-anaphylaxis in adults, while the most common triggers in children were seafood, egg, and cow's milk. When compared to children, adults with food-induced anaphylaxis were more likely to present with cardiovascular and neurological symptoms. A significant proportion of both adults and children with food-induced anaphylaxis did not receive epinephrine in real-world practice. |
| Date: | 2023-12-28 |
| Relation: | Allergy. 2023 Dec 28;78(Suppl. 112):523. |
| Link to: | http://dx.doi.org/10.1111/all.15925 |
| JIF/Ranking 2023: | http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0105-4538&DestApp=IC2JCR |
| Appears in Collections: | [蔡慧如] 會議論文/會議摘要
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| ISI001144363000463.pdf | | 178Kb | Adobe PDF | 37 | View/Open |
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