國家衛生研究院 NHRI:Item 3990099045/15607
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    题名: Systemic treatments in pancreatic cancer: Taiwan pancreas society recommendation
    作者: Su, YY;Chiang, NJ;Chiu, TJ;Huang, CJ;Hsu, SJ;Lin, HC;Yang, SH;Yang, Y;Chou, WC;Chen, YY;Bai, LY;Li, CP;Chen, JS
    贡献者: National Institute of Cancer Research
    摘要: Pancreatic cancer is a highly aggressive malignancy with a poor prognosis. Over the past decade, significant therapeutic advancements have improved the survival rates of patients with pancreatic cancer. One of the primary factors contributing to these positive outcomes is the evolution of chemotherapy, from monotherapy to doublet or triplet regimens, and the integration of multimodal approaches. Additionally, targeted agents tailored to patients with specific genetic alterations and the development of cell therapies show promise in benefiting certain subpopulations. This article focuses on examining pivotal studies that explore the role of chemotherapy in neoadjuvant, adjuvant, maintenance, and salvage settings; highlights interesting findings related to cell therapy; and provides an overview of ongoing trials concerning metastatic settings. This review primarily aimed to offer recommendations based on therapeutic evidence, recent advancements in new treatment combinations, and the most innovative approaches. A unique aspect of this review is the inclusion of published papers on clinical trials and real-world data in Taiwan, thus adding a valuable perspective to the overall analysis.
    日期: 2024-06
    關聯: Biomedical Journal. 2024 Jun;47(3):Article number 100696.
    Link to: http://dx.doi.org/10.1016/j.bj.2023.100696
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=2319-4170&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:001283075800001
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85185104684
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