國家衛生研究院 NHRI:Item 3990099045/15567
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/15567


    Title: Association between Cesarean section delivery and increased risk of childhood Kawasaki disease
    Authors: Wei, CF;Chen, MH;Lin, CC;Tsai, MS;Guo, YL;Lin, SJ;Wu, MH;Hsieh, WS;Chen, PC
    Contributors: Institute of Population Health Sciences;National Institute of Environmental Health Sciences
    Abstract: Aim: Cesarean section delivery is associated with microbiota disruption and immuno-dysregulation during childhood, but the association with Kawasaki disease remains uncertain. We aimed to evaluate the association between Cesarean section and Kawasaki disease. Methods: We examined the association between Kawasaki disease between six and eighteen months and Cesarean section within a birth cohort of 15,796 mother-infant pairs in Taiwan. The associations were assessed with Poisson regression in the study population, in the 1:2 propensity score-matched subpopulation, and compared with febrile convulsion, trauma and accidents during the same interval as negative control outcomes. Results: Cesarean section was found to increase the risk of Kawasaki disease among overall population (adjusted relative risk [aRR]: 2.22, 95 % confidence interval (CI): 1.14–4.34) and the matched subpopulation (aRR: 2.29, 95 % CI: 1.14–4.68 in PS-matched subpopulation). Meanwhile, there was no association between Cesarean section and the clinic visits for febrile convulsion, trauma and accidents. Conclusion: In conclusion, this study identified a potential association between Cesarean section delivery and a higher risk of Kawasaki disease during six-to eighteen months of the prospective birth cohort in Taiwan.
    Date: 2024-08
    Relation: Journal of the Formosan Medical Association. 2024 Aug;123(8):843-848.
    Link to: http://dx.doi.org/10.1016/j.jfma.2023.12.006
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0929-6646&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:001290632600001
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85180500960
    Appears in Collections:[Mei-Huei Chen] Periodical Articles
    [Yue-Liang Guo] Periodical Articles
    [Pau-Chung Chen] Periodical Articles

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