國家衛生研究院 NHRI:Item 3990099045/15553
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/15553


    Title: CKD of unknown etiology: Is Taiwan another hotspot?
    Authors: Amante, IDT;Lin, MY;Hwang, SJ
    Contributors: Institute of Population Health Sciences
    Abstract: Chronic kidney disease (CKD) is fast becoming a global health problem forecasted to reach epidemic proportions over the next few decades.1 In 2022, it was reported to affect >10% of the world’s population or approximately 840 million individuals.2 Although diabetes, hypertension, smoking, and obesity are well-known risk factors; causes of CKD in developing countries are not as well delineated. According to the most recent survey in India, above 70% of patients with CKD could be defined as CKD of unknown etiology (CKDu).3 The first formal mention of a possible new pathogenic entity for CKD and ESKD was published in 2002 by Trabanino et al.,4 who also reported that over 70% of the population with advanced CKD in El Salvador had a disease of unknown origin. Since 2006, international workshops under SALTRA, a program on Health and Work in Central America, began to recognize an abnormal prevalence of CKDu in Central America. It was characterized as a progressive decline in GFR of otherwise asymptomatic individuals, predominantly men, aged 20 to 60 years, working mostly in sugarcane and cotton plantations along the coasts of El Salvador and Nicaragua. At the time, it was termed Mesoamerican Nephropathy.5 In the 1990s, similar epidemics were reported in the North-Central province of Sri Lanka (Sri Lankan nephropathy), Andhra Pradesh of India (Uddanam nephropathy), and in countries such as Egypt and Tunisia.6 Although the majority of the studies are centered in Central America, it is yet to be known if the reports from other parts of the world are the same disease condition.
    Date: 2024-01
    Relation: Kidney International Reports. 2024 Jan;9(1):4-6.
    Link to: http://dx.doi.org/10.1016/j.ekir.2023.11.014
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=2468-0249&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:001165969500001
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85178561792
    Appears in Collections:[Others] Periodical Articles

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