國家衛生研究院 NHRI:Item 3990099045/1532
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    题名: Relapsing Mooren's ulcer after amniotic membrane transplantation combined with conjunctival autografting
    作者: Chen, KH;Hsu, WM;Liang, CK
    贡献者: Division of Medical Engineering Research
    摘要: Purpose: To report a patient with Mooren's ulcer that relapsed 2 months after amniotic membrane (AM) transplantation and conjunctival autografting and its subsequent retreatment. Design: Interventional case report. Methods: We performed multilayered AM transplantation and conjunctival autografting from the opposite healthy eye to treat a corneoscleral perforation caused by Mooren's ulcer in a 60-year-old woman. Main Outcome Measures: Reformation of the anterior chamber, absence of inflammation, and restoration of visual acuity. Results: The perforated corneoscleral lesion was sealed successfully by the AM and conjunctiva graft and led to a stable condition for 2 months. Relapsing corneal edema, keratic precipitates, and cell infiltration occurred along the margin of the conjunctival graft with severe vessel engorgement. After removing the conjunctival graft and regrafting of additional AM, the lesion subsided for at least 1 year. Conclusions: Amniotic membrane transplants may be useful in treating corneal perforation of immunologic origin, but conjunctiva and its vessels may play a role in the process of peripheral corneal destruction of Mooren's ulcer. (C) 2004 by the American Academy of Ophthalmology.
    关键词: Ophthalmology
    日期: 2004-04
    關聯: Ophthalmology. 2004 Apr;111(4):792-795.
    Link to: http://dx.doi.org/10.1016/j.ophtha.2003.06.024
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0161-6420&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000220613300025
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=1842423149
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