國家衛生研究院 NHRI:
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    Patents [0/23]
    Periodical Articles [37/38]
    Conference Papers/Meeting Abstract [4/5]

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    Showing items 1-10 of 66. (7 Page(s) Totally)
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    DateTitleRelation
    2021-08-12 Xanthine derivatives reveal an allosteric binding site in methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) Journal of Medicinal Chemistry. 2021 Aug 12;64(15):11288-11301.
    2021-08-01 DBPR108, a novel dipeptidyl peptidase-4 inhibitor with antihyperglycemic activity Life Sciences. 2021 Aug 1;278:Article number 119574.
    2021-01 Potent and orally active purine-based fetal hemoglobin inducers for treating Beta-thalassemia and sickle cell disease European Journal of Medicinal Chemistry. 2021 Jan;209:Article number 112938.
    2019-12 Identification of a multitargeted tyrosine kinase inhibitor for the treatment of gastrointestinal stromal tumors and acute myeloid leukemia Journal of Medicinal Chemistry. 2019 Dec;62(24):11135-11150.
    2019-07 Use of integrated genomic analyses in patient-derived tumor model to discover new clinical indications for the multikinase inhibitor drug candidate, DBPR216 Cancer Research. 2019 Jul;79(13, Suppl.):Abstract number 4626.
    2019-05-28 Identification of novel anti-liver cancer small molecules with better therapeutic index than sorafenib via zebrafish drug screening platform Cancers. 2019 May 28;11(6):Article number 739.
    2019-04-10 Discovery of Conformational Control Inhibitors Switching off the Activated c-KIT and Targeting a Broad Range of Clinically Relevant c-KIT Mutants Journal of Medicinal Chemistry. 2019 Apr 10;62(8):3940-3957.
    2018-08-24 BPR1J373, a novel multitargeted kinase inhibitor, effectively suppresses the growth of gastrointestinal stromal tumor Cancer Science. 2018 Nov;109(11):3591-3601.
    2016-12 Novel cKIT kinase inhibitor, BPRCKJ001, as an advanced therapeutic candidate for GIST Annals of Oncology. 2016 Dec;27(Suppl. 9):Meeting Abstract 2P.
    2016-10 BPR1J373, an oral multiple tyrosine kinase inhibitor, targets c-KIT for the treatment of c-KIT driven myeloid leukemia Molecular Cancer Therapeutics. 2016 Oct;15(10):2323-2333.

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