國家衛生研究院 NHRI:Item 3990099045/1473

NHRI > Institute of Biomedical Engineering and Nanomedicine > Ned H. C. Hwang(2000-2008) > Periodical Articles > Item 3990099045/1473

Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/1473

Title:	Development of squeeze flow in mechanical heart valve: A particle image velocimetry investigation
Authors:	Zhang, P;Yeo, JH;Hwang, NHC
Contributors:	Division of Medical Engineering Research
Abstract:	Fluid between the reducing flow channel of the valve occluder and the orifice wall tends to be squeezed out of the flow channel, causing a high-speed flow. The squeeze flow is accompanied by a sharp local pressure drop, which may result in potential cavitation phenomenon in a mechanical heart valve (MHV). Limited experimental investigation has been conducted into the flow physics of this squeeze flow phenomenon, which is likely to be the origin of MHV cavitation. We used a pulsatile test loop simulating physiologic flow conditions and an actual-size transparent MHV model for flow visualization. A digital particle image velocimetry (DPIV) system incorporated with a microscope was applied to observe flow within a narrowing channel. A triggering mechanism was designed so that the DPIV system could be timed to capture images when the valve occluder was near its closing position. A series of images within the channel from,, 1.4 to 0.1 mm were captured. As the gap between the tip of the valve occluder and orifice wall becomes narrower, evidence of high-speed jet flow becomes more apparent. When the flow channel is reduced to around 0.1 mm, flow velocity of up to 2 m/s was noted. A sudden increase in high-speed jet flow causes a corresponding reduction in local pressure, and is a likely source for potential cavitation.
Keywords:	Engineering, Biomedical;Transplantation
Date:	2006-07
Relation:	ASAIO Journal. 2006 Jul-Aug;52(4):391-397.
Link to:	http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?an=00002480-200607000-00007
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1058-2916&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000239255700007
Cited Times(Scopus):	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=33746783757
Appears in Collections:	[Ned H. C. Hwang(2000-2008)] Periodical Articles

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