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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/1469


    Title: Statistical correlation between transient pressure drop and cavitation at closure of a mechanical heart valve
    Authors: Wu, CF;Liu, JS;Hwang, NHC;Lin, YKM
    Contributors: Division of Medical Engineering Research
    Abstract: Cavitation on a mechanical heart valve (MHV) is attributable to transient regional pressure drop at the instant of valve closure. As a cavitation bubble collapses, it emits shock waves, which have the characteristics of high frequency oscillations (HFO) on a pressure time trace. The potential for such HFO bursts to cause material damage on an MHV can be measured by the cavitation impulse 1, which is defined as the area under the trace of the HFO bursts. In the present study, experiments were conducted on a bileaflet MHV in a durability tester, operated at pulse rates from 300-1,000 bpm. In each case, the transient pressure near an occluder was monitored for 60,000 beats via a transducer. The peak pressure drop P. and the corresponding cavitation impulse I obtained for the 60,000 beat sequence are found to resemble sample records of two stationary stochastic processes, each of which follows a log normal distribution. Their first order probability density functions are estimated from the records. The correlation is investigated between I and P. associated with each beat, which is found to be of statistical significance.
    Keywords: Engineering, Biomedical;Transplantation
    Date: 2005-01
    Relation: ASAIO Journal. 2005 Jan-Feb;51(1):11-16.
    Link to: http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?an=00002480-200501000-00003
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1058-2916&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000226620400003
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=12844253699
    Appears in Collections:[黃煥常(2000-2008)] 期刊論文

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