國家衛生研究院 NHRI:Item 3990099045/14411

NHRI > Institute of Population Health Sciences > Meng-Chih Lee > Periodical Articles > Item 3990099045/14411

Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/14411

Title:	Effect of maternal hypertensive disorders during pregnancy on offspring's early childhood body weight: A population-based cohort study
Authors:	Huang, YD;Luo, YR;Lee, MC;Yeh, CJ
Contributors:	Institute of Population Health Sciences
Abstract:	Objective: The prevalence of hypertensive disorder during pregnancy (HDP) and childhood obesity is increasing worldwide. HDP or obesity in mothers can increase the risk of overweight/obesity (OWOB) in their children. Few longitudinal studies have examined the associations of maternal body weight with the growth and risk factors for overweight in infants born to mothers with HDP. This study examined the risk factors for childhood OWOB through the age of 66 months in children born to mothers with HDP. Materials and methods: In total, 24,200 pairs of mothers and their children were selected from the Taiwan Birth Cohort Study. The children's body weights were classified and analyzed to determine infant growth at birth and at the ages of 12, 24, 36, and 66 months. Multiple logistic regression analyses with different model settings were performed to identify the factors affecting growth and childhood OWOB in the children of mothers with HDP. Results: The average birth weight of children was lower in the HDP group than in the non-HDP group. The catch-up phenomenon began at the age of 18 months. The incidence of OWOB was higher in the children in the HDP group than in those in the non-HDP group from the age of 24 months and increased with the children's age. At every age point, maternal overweight before pregnancy was the main risk factor for childhood OWOB, and this effect increased with the children's age (odds ratio [OR]: 1.83 at 66 months). The effect of excessive maternal gestational weight gain on childhood OWOB was significant (OR: 1.26–1.44 for various age points). Conclusion: Maternal overweight is the main risk factor for OWOB in children born to mothers with HDP. After adjusting for related confounders, we determined that HDP did not exert a significant effect on the risk of childhood OWOB.
Date:	2022-09
Relation:	Taiwanese Journal of Obstetrics and Gynecology. 2022 Sep;61(5):761-767.
Link to:	http://dx.doi.org/10.1016/j.tjog.2022.01.003
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1028-4559&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000863062700008
Cited Times(Scopus):	https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85134811636
Appears in Collections:	[Meng-Chih Lee] Periodical Articles

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