國家衛生研究院 NHRI:Item 3990099045/14357
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 12145/12927 (94%)
造访人次 : 857472      在线人数 : 548
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 查询小技巧：
  • 您可在西文检索词汇前后加上"双引号"，以获取较精准的检索结果
  • 若欲以作者姓名搜寻，建议至进阶搜寻限定作者字段，可获得较完整数据
    •  进阶搜寻
    主页 ‧ 登入 ‧ 上传 ‧ 说明 ‧ 关于NHRI ‧ 管理 到手机版


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/14357


    题名: PM2.5 exposure and risk of lung adenocarcinoma in women of Taiwan: A case–control study with density sampling
    作者: Yang, SC;Lin, FY;Wu, TI;Wu, CD;Wang, JD
    贡献者: National Institute of Environmental Health Sciences
    摘要: Background and objective: The prevalence of smoking among women in Taiwan is <5%, but the incidence of lung cancer remains high. This study determined the association between PM2.5 (fine particulate matter with an aerodynamic diameter of ≤2.5 μm) exposure and lung cancer among women in Taiwan. Methods: In total, 21,301 female lung cancer cases nationwide were newly diagnosed between 2012 and 2017. Each case was age-, sex- and calendar year-matched with four controls randomly selected from the general population. Allowing a latent period of 5 years, we estimated the PM2.5 and nitrogen dioxide (NO2) exposures for each individual according to the residential changes from 2000. We adopted self-reported smoking statuses for the cases, while those of controls were estimated using annual surveys in each residential county. We performed multiple logistic regression analyses to examine the associations between PM2.5 and NO2 exposures and incident lung cancer cases. Results: The ORs of lung adenocarcinoma for the third (30.5–35.1 μg/m3), fourth (35.1–39.3 μg/m3) and fifth PM2.5 exposure quintiles (39.3–48.1 μg/m3) relative to the first quintile were 1.10 (95% CI: 1.04–1.16), 1.12 (95% CI: 1.06–1.19) and 1.10 (95% CI: 1.04–1.16), respectively, after adjusting for smoking, residence and comorbidities. A dose–response relationship (p = 0.004) was found. The associations persisted with a 10-year latency and were not detected for small-cell and squamous cell carcinoma after control for smoking. We did not observe a similar effect for NO2 exposure. Conclusion: Residential PM2.5 exposure higher than 30 μg/m3 was associated with an increased risk of lung adenocarcinoma in women of Taiwan.
    日期: 2022-11
    關聯: Respirology. 2022 Nov;27(11):951-958.
    Link to: http://dx.doi.org/10.1111/resp.14316
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1323-7799&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000814943300001
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85132591253
    显示于类别:[其他] 期刊論文

    文件中的档案:

    档案 描述 大小格式浏览次数
    SCP85132591253.pdf515KbAdobe PDF180检视/开启


    在NHRI中所有的数据项都受到原著作权保护.

    TAIR相关文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈