國家衛生研究院 NHRI:Item 3990099045/14311

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Title:	The anti-atherosclerotic effects of natural polysaccharides: From phenomena to the main mechanisms of action
Authors:	V, PK;V, IS;Yet, SF;A, NO
Contributors:	Institute of Cellular and Systems Medicine
Abstract:	Polysaccharides (PSs) of plant origin have a variety of biological activities, anti-atherosclerotic including, but their use in atherosclerosis therapy is hindered by insufficient knowledge on the cellular and molecular mechanisms of action. In this review, the influence of several natural PSs on the function of macrophages, viral activity, and macrophage cholesterol metabolism has been discussed considering the tight interplay between these aspects in the pathogenesis of atherosclerosis. The anti-atherosclerotic activities of natural PSs related to other mechanisms have been also explored. Directions for further research of anti-atherosclerotic effects of natural PSs have been outlined, the most promising of which can be nutrigenomic studies.
Date:	2022-06-28
Relation:	Current Pharmaceutical Design. 2022 Jun 28;28(22):1823-1832.
Link to:	http://dx.doi.org/10.2174/1381612828666220518095025
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1381-6128&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000852809400005
Cited Times(Scopus):	https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85137134870
Appears in Collections:	[Shaw-Fang Yet] Periodical Articles

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