國家衛生研究院 NHRI:
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    最後更新時間: 2024-12-01 09:16


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    日期題名關聯
    2024-04 BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase inhibitor, inhibits SARS-CoV-2 variants of concern and exerts synergistic antiviral activity in combination with remdesivir Antimicrobial Agents and Chemotherapy. 2024 Apr 3;68(4):Article number e0095623
    2021-06-16 Discovery of an orally efficacious MYC inhibitor for liver cancer using a GNMT-based high-throughput screening system and structure-activity relationship analysis Journal of Medicinal Chemistry. 2021 Jun 16;64(13):8992-9009.
    2016-12 Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation Oncotarget. 2016 Dec;7(52):86239-86256.
    2016-11-29 Discovery of novel inhibitors of Aurora kinases with indazole scaffold: In silico fragment-based and knowledge-based drug design European Journal of Medicinal Chemistry. 2016 Nov 29;124:186-199.
    2015-06-29 Homology modeling of DFG-in FMS-like tyrosine kinase 3 (FLT3) and structure-based virtual screening for inhibitor identification Scientific Reports. 2015 Jun 29;5:Article number 11702.
    2014-10 Small-molecule EGFR tyrosine kinase inhibitors for the treatment of cancer Expert Opinion on Investigational Drugs. 2014 Oct;23(10):1333-1348.
    2014-08 Ligand efficiency based approach for efficient virtual screening of compound libraries European Journal of Medicinal Chemistry. 2014 Aug;83:226-235.
    2014-07 Anaplastic lymphoma kinase (ALK) inhibitors: A review of design and discovery MedChemComm. 2014 Jul;5(9):1266-1279.
    2013-01 3D-QSAR-assisted drug design: Identification of a potent quinazoline-based aurora kinase inhibitor ChemMedChem. 2013 Jan;8(1):136-148.

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