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Institute of Biotechnology and Pharmaceutical Research
Wen-Chieh Wang
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BPR3P0128, a non-nucleoside RNA-dep...
Discovery of an orally efficacious ...
Discovery of BPR1K871, a quinazolin...
Homology modeling of DFG-in FMS-lik...
Anaplastic lymphoma kinase (ALK) in...
Ligand efficiency based approach fo...
Small-molecule EGFR tyrosine kinase...
3D-QSAR-assisted drug design: Ident...
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Showing items 1-9 of 9. (1 Page(s) Totally)
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Date
Title
Relation
2024-04
BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase inhibitor, inhibits SARS-CoV-2 variants of concern and exerts synergistic antiviral activity in combination with remdesivir
Antimicrobial Agents and Chemotherapy. 2024 Apr 3;68(4):Article number e0095623
2021-06-16
Discovery of an orally efficacious MYC inhibitor for liver cancer using a GNMT-based high-throughput screening system and structure-activity relationship analysis
Journal of Medicinal Chemistry. 2021 Jun 16;64(13):8992-9009.
2016-12
Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation
Oncotarget. 2016 Dec;7(52):86239-86256.
2016-11-29
Discovery of novel inhibitors of Aurora kinases with indazole scaffold: In silico fragment-based and knowledge-based drug design
European Journal of Medicinal Chemistry. 2016 Nov 29;124:186-199.
2015-06-29
Homology modeling of DFG-in FMS-like tyrosine kinase 3 (FLT3) and structure-based virtual screening for inhibitor identification
Scientific Reports. 2015 Jun 29;5:Article number 11702.
2014-10
Small-molecule EGFR tyrosine kinase inhibitors for the treatment of cancer
Expert Opinion on Investigational Drugs. 2014 Oct;23(10):1333-1348.
2014-08
Ligand efficiency based approach for efficient virtual screening of compound libraries
European Journal of Medicinal Chemistry. 2014 Aug;83:226-235.
2014-07
Anaplastic lymphoma kinase (ALK) inhibitors: A review of design and discovery
MedChemComm. 2014 Jul;5(9):1266-1279.
2013-01
3D-QSAR-assisted drug design: Identification of a potent quinazoline-based aurora kinase inhibitor
ChemMedChem. 2013 Jan;8(1):136-148.
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